Medicinal chemistry
Drug design 
 Drug discovery
Drug discovery hit to lead
 Druglikeness
Biological activity Biological target
High-throughput screening  Lead compound
Lipinski's Rule of Five Medicinal chemistry
Molecular design software Pharmacophore
Quantitative structure-activity relationship Pharmacology
Peptidomimetic Protein
ADME
ADME Bioavailability
Biopharmaceutics Classification System  Caco-2
Chemical property Distribution
Drug metabolism Excretion
Partition coefficient  Pharmacodynamics
Polar surface area
Biological target
Agonist Allosteric regulation
Biological target Channel blocker
Enzyme Enzyme activator
Enzyme inhibitor G protein-coupled receptor
Inverse agonist Ligand-gated ion channe
NMDA receptor antagonist Noncovalent bonding
Nuclear receptor Protein kinase
Receptor antagonist Voltage-gated ion channel
Example of drug and therapeutic target
5-HT3 antagonist Benzodiazepine
Cannabinoid receptor antagonist Development of dipeptidyl peptidase-4 inhibitors
Discovery and development of CCR5 receptor antagonists Discovery and development of TRPV1 antagonists 
Discovery and development of angiotensin receptor blockers Discovery and development of cyclooxygenase 2 inhibitors
Glycine receptor  Kainate receptor
NK1 receptor antagonist Nicotinic agonist 
Nicotinic antagonist P2X purinoreceptor 
Triptans: Drug Discovery and Development