Journal of Medicinal Chemistry

Discovery of Potent Heterodimeric Antagonists of Inhibitor of Apoptosis Proteins (IAPs) with Sustained Antitumor Activity (Fri, 23 Jan 2015)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm501482t
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Novel 3-Nitrotriazole-Based Amides and Carbinols as Bifunctional Antichagasic Agents (Fri, 23 Jan 2015)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm5015742
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Development of a Series of Aryl Pyrimidine Kynurenine Monooxygenase Inhibitors as Potential Therapeutic Agents for the Treatment of Huntington’s Disease (Fri, 23 Jan 2015)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm501350y
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Antibacterial Drug Leads: DNA and Enzyme Multitargeting (Thu, 22 Jan 2015)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm501449u
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Small Molecule Discoidin Domain Receptor Kinase Inhibitors and Potential Medical Applications (Wed, 21 Jan 2015)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm5012319
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Exploration of Cyanine Compounds as Selective Inhibitors of Protein Arginine Methyltransferases: Synthesis and Biological Evaluation (Wed, 21 Jan 2015)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm501452j
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A High-Throughput Screen Reveals New Small-Molecule Activators and Inhibitors of Pantothenate Kinases (Wed, 21 Jan 2015)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm501585q
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Identification of the Minimum Peptide from Mouse Myostatin Prodomain for Human Myostatin Inhibition (Wed, 21 Jan 2015)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm501170d
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Cell-Permeable Inhibitors of Neuronal Nitric Oxide Synthase Open New Prospects for the Treatment of Neurological Disorders (Tue, 20 Jan 2015)
Journal of Medicinal Chemistry DOI: 10.1021/acs.jmedchem.5b00057
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SAR-Guided Development and Characterization of a Potent Antitumor Compound toward B-Cell Neoplasms with No Detectable Cytotoxicity toward Healthy Cells (Tue, 20 Jan 2015)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm501848m
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Promiscuous 2-Aminothiazoles (PrATs): A Frequent Hitting Scaffold (Fri, 16 Jan 2015)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm501402x
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Design, Synthesis, and Biological Evaluation of Tetrazole Analogs of Cl-Amidine as Protein Arginine Deiminase Inhibitors (Fri, 16 Jan 2015)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm501636x
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Stemistry: The Control of Stem Cells in Situ Using Chemistry (Thu, 15 Jan 2015)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm500838d
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Computational Methods for Medicinal Chemistry (Wed, 14 Jan 2015)
Journal of Medicinal Chemistry DOI: 10.1021/acs.jmedchem.5b00053
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Fragment-Based Drug Discovery of 2-Thiazolidinones as BRD4 Inhibitors: 2. Structure-Based Optimization (Wed, 14 Jan 2015)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm501504k
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Highly Selective Salicylketoxime-Based Estrogen Receptor β Agonists Display Antiproliferative Activities in a Glioma Model (Wed, 14 Jan 2015)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm501829f
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Discovery of 1H-Pyrazol-3(2H)-ones as Potent and Selective Inhibitors of Protein Kinase R-like Endoplasmic Reticulum Kinase (PERK) (Wed, 14 Jan 2015)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm5017494
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Nintedanib: From Discovery to the Clinic (Wed, 14 Jan 2015)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm501562a
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Effect of Size and N-Terminal Residue Characteristics on Bacterial Cell Penetration and Antibacterial Activity of the Proline-Rich Peptide Bac7 (Wed, 14 Jan 2015)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm501367p
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Synthesis and Evaluation of Series of Diazine-Bridged Dinuclear Platinum(II) Complexes through in Vitro Toxicity and Molecular Modeling: Correlation between Structure and Activity of Pt(II) Complexes (Tue, 13 Jan 2015)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm5017686
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Organic Carbamates in Drug Design and Medicinal Chemistry (Wed, 07 Jan 2015)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm501371s
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CNS Drug Design: Balancing Physicochemical Properties for Optimal Brain Exposure (Tue, 06 Jan 2015)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm501535r
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Novel 2,4-Disubstituted Pyrimidines as Potent, Selective, and Cell-Permeable Inhibitors of Neuronal Nitric Oxide Synthase (Mon, 29 Dec 2014)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm501719e
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Targeting DNA Methylation with Small Molecules: What’s Next? (Thu, 04 Dec 2014)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm500843d
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Parallel Worlds of Public and Commercial Bioactive Chemistry Data (Thu, 04 Dec 2014)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm5011308
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Selective Inhibitors of Protein Methyltransferases (Tue, 02 Dec 2014)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm501234a
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Targeting Aldose Reductase for the Treatment of Diabetes Complications and Inflammatory Diseases: New Insights and Future Directions (Mon, 17 Nov 2014)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm500907a
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Inhibiting the Deubiquitinating Enzymes (DUBs) (Fri, 14 Nov 2014)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm501061a
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Small-Molecule Inhibitors of the MDM2–p53 Protein–Protein Interaction (MDM2 Inhibitors) in Clinical Trials for Cancer Treatment (Fri, 14 Nov 2014)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm501092z
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Glucagon-like Peptide-1 (GLP-1) Analogs: Recent Advances, New Possibilities, and Therapeutic Implications (Thu, 13 Nov 2014)
TOC Graphic Journal of Medicinal Chemistry DOI: 10.1021/jm500810s
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