ACS Chemical Biology

Repair of a Site-Specific DNA Cleavage: Old-School Lessons for Cas9-Mediated Gene Editing (Tue, 14 Nov 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00760
>> Read More

Microfluidic-Enabled Intracellular Delivery of Membrane Impermeable Inhibitors to Study Target Engagement in Human Primary Cells (Mon, 13 Nov 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00683
>> Read More

Structure–Activity Relationships of the S-Linked Glycocin Sublancin (Fri, 10 Nov 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00819
>> Read More

Profiling of Protein O-GlcNAcylation in Murine CD8+ Effector- and Memory-like T Cells (Fri, 10 Nov 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00869
>> Read More

Turn-on Fluorene Push–Pull Probes with High Brightness and Photostability for Visualizing Lipid Order in Biomembranes (Wed, 08 Nov 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00658
>> Read More

Using a Specific RNA–Protein Interaction To Quench the Fluorescent RNA Spinach (Wed, 08 Nov 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00332
>> Read More

Global Awakening of Cryptic Biosynthetic Gene Clusters in Burkholderia thailandensis (Wed, 08 Nov 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00681
>> Read More

Tuning the Color Palette of Fluorescent Copper Sensors through Systematic Heteroatom Substitution at Rhodol Cores (Tue, 07 Nov 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00748
>> Read More

Ebselen: Mechanisms of Glutamate Dehydrogenase and Glutaminase Enzyme Inhibition (Tue, 07 Nov 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00728
>> Read More

Luciferase Activity of Insect Fatty Acyl-CoA Synthetases with Synthetic Luciferins (Tue, 07 Nov 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00813
>> Read More

Photocontrol of the Hv1 Proton Channel (Tue, 07 Nov 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00523
>> Read More

Large Scale Mutational and Kinetic Analysis of a Self-Hydrolyzing Deoxyribozyme (Fri, 03 Nov 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00621
>> Read More

Insights into Interactions of Mycobacteria with the Host Innate Immune System from a Novel Array of Synthetic Mycobacterial Glycans (Fri, 03 Nov 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00797
>> Read More

Development of 5N-Bicalutamide, a High-Affinity Reversible Covalent Antiandrogen (Thu, 02 Nov 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00702
>> Read More

Rewiring of the Austinoid Biosynthetic Pathway in Filamentous Fungi (Thu, 02 Nov 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00814
>> Read More

Enthalpy-Based Screening of Focused Combinatorial Libraries for the Identification of Potent and Selective Ligands (Thu, 02 Nov 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00717
>> Read More

CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine (Tue, 24 Oct 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00657
>> Read More

The Promise and Challenge of In Vivo Delivery for Genome Therapeutics (Thu, 19 Oct 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00680
>> Read More

Genome Editing: Insights from Chemical Biology to Support Safe and Transformative Therapeutic Applications (Wed, 18 Oct 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00689
>> Read More

Profiling Cytidine Acetylation with Specific Affinity and Reactivity (Tue, 17 Oct 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00734
>> Read More

Editing the Genome Without Double-Stranded DNA Breaks (Mon, 09 Oct 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00710
>> Read More

Two-Color 810 nm STED Nanoscopy of Living Cells with Endogenous SNAP-Tagged Fusion Proteins (Mon, 02 Oct 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00616
>> Read More

A Single-Chain Photoswitchable CRISPR-Cas9 Architecture for Light-Inducible Gene Editing and Transcription (Fri, 29 Sep 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00603
>> Read More

Discovery of Oligonucleotide Signaling Mediated by CRISPR-Associated Polymerases Solves Two Puzzles but Leaves an Enigma (Wed, 27 Sep 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00713
>> Read More

CRISPR-Mediated Tagging of Endogenous Proteins with a Luminescent Peptide (Thu, 21 Sep 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00549
>> Read More

Rheostatic Control of Cas9-Mediated DNA Double Strand Break (DSB) Generation and Genome Editing (Fri, 15 Sep 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00652
>> Read More

Multidimensional Control of Cas9 by Evolved RNA Polymerase-Based Biosensors (Tue, 22 Aug 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00532
>> Read More

Chemically-Modified Peptides Targeting the PDZ Domain of GIPC as a Therapeutic Approach for Cancer (Tue, 10 Mar 2015)
ACS Chemical Biology DOI: 10.1021/cb500865a
>> Read More

Site Search