ACS Chemical Biology



[ASAP] Subtle Control of Carbon Chain Length in Polyunsaturated Fatty Acid Synthases (Fri, 15 Nov 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00803
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[ASAP] Identification and Mobilization of a Cryptic Antibiotic Biosynthesis Gene Locus from a Human-Pathogenic <italic toggle="yes">Nocardia</italic> Isolate (Thu, 14 Nov 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00763
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[ASAP] Immunity-Guided Identification of Threonyl-tRNA Synthetase as the Molecular Target of Obafluorin, a ß-Lactone Antibiotic (Thu, 14 Nov 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00590
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[ASAP] Addition of Isocyanide-Containing Amino Acids to the Genetic Code for Protein Labeling and Activation (Thu, 14 Nov 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00678
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[ASAP] Employing a ZTP Riboswitch to Detect Bacterial Folate Biosynthesis Inhibitors in a Small Molecule High-Throughput Screen (Thu, 14 Nov 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00713
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[ASAP] Dimensionally Enhanced Antibacterial Library Screening (Wed, 13 Nov 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00745
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[ASAP] Targeting Regorafenib-Induced Toxicity through Inhibition of Gut Microbial ß-Glucuronidases (Tue, 12 Nov 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00663
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[ASAP] Lost in (Clinical) Translation: Recent Advances in Heparin Neutralization and Monitoring (Tue, 12 Nov 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00772
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[ASAP] Mutations of Triad Determinants Changes the Substrate Alignment at the Catalytic Center of Human ALOX5 (Tue, 12 Nov 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00674
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[ASAP] Deciphering the Antitoxin-Regulated Bacterial Stress Response via Single-Cell Analysis (Mon, 11 Nov 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00721
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[ASAP] ABHD2 Inhibitor Identified by Activity-Based Protein Profiling Reduces Acrosome Reaction (Thu, 07 Nov 2019)
ACS Chemical Biology DOI: 10.1021/acschembio.9b00824
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[ASAP] The ARH and Macrodomain Families of a-ADP-ribose-acceptor Hydrolases Catalyze a-NAD<sup><bold>+</bold></sup> Hydrolysis (Wed, 06 Nov 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00429
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[ASAP] <italic toggle="yes">N</italic>-Benzyl Derivatives of Long-Chained 4-Amino-7-chloro-quionolines as Inhibitors of Pyocyanin Production in <italic toggle="yes">Pseudomonas aeruginosa</italic> (Mon, 04 Nov 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00682
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[ASAP] Surprising Non-Additivity of Methyl Groups in Drug–Kinase Interaction (Mon, 04 Nov 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00476
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[ASAP] Archaeal Glycolipid S-TGA-1 Is Crucial for Trimer Formation and Photocycle Activity of Bacteriorhodopsin (Mon, 04 Nov 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00756
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[ASAP] Leveraging New Definitions of the LxVP SLiM To Discover Novel Calcineurin Regulators and Substrates (Fri, 01 Nov 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00606
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[ASAP] Production of a Dibrominated Aromatic Secondary Metabolite by a Planctomycete Implies Complex Interaction with a Macroalgal Host (Fri, 01 Nov 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00641
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[ASAP] Engineered Reader Proteins for Enhanced Detection of Methylated Lysine on Histones (Fri, 01 Nov 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00651
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[ASAP] Cytosolic Delivery of Macromolecules in Live Human Cells Using the Combined Endosomal Escape Activities of a Small Molecule and Cell Penetrating Peptides (Thu, 31 Oct 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00585
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[ASAP] Dual Inhibitors of 8-Oxoguanine Surveillance by OGG1 and NUDT1 (Tue, 29 Oct 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00490
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[ASAP] R-BIND: An Interactive Database for Exploring and Developing RNA-Targeted Chemical Probes (Tue, 29 Oct 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00631
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[ASAP] Quantitative Analysis of the Substrate Specificity of Human Rhinovirus 3C Protease and Exploration of Its Substrate Recognition Mechanisms (Tue, 29 Oct 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00539
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[ASAP] A Unique Conformational Distortion Mechanism Drives Lipocalin 2 Binding to Bacterial Siderophores (Mon, 28 Oct 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00820
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[ASAP] Synthetic Chemical Probes That Dissect Vitamin D Activities (Mon, 28 Oct 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00718
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[ASAP] Correction to Directed Evolution of Split APEX2 Peroxidase (Mon, 28 Oct 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00798
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[ASAP] A Point of Inflection and Reflection on Systems Chemical Biology (Mon, 28 Oct 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00714
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[ASAP] Discovery of a Celecoxib Binding Site on Prostaglandin E Synthase (PTGES) with a Cleavable Chelation-Assisted Biotin Probe (Fri, 25 Oct 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00511
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[ASAP] Structure-Dependent Modulation of Substrate Binding and Biodegradation Activity of Pirin Proteins toward Plant Flavonols (Wed, 23 Oct 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00575
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[ASAP] Discovery of Interacting Proteins of ABA Receptor PYL5 <italic toggle="yes">via</italic> Covalent Chemical Capture (Tue, 22 Oct 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00806
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[ASAP] Histidine-Mediated Intramolecular Electrostatic Repulsion for Controlling pH-Dependent Protein–Protein Interaction (Tue, 22 Oct 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00652
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[ASAP] Toward a Rational Approach to Design Split G-Quadruplex Probes (Tue, 22 Oct 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00634
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[ASAP] Transcriptional Bypass of DNA–Protein and DNA–Peptide Conjugates by T7 RNA Polymerase (Mon, 21 Oct 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00365
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[ASAP] Development of Small Molecule Chimeras That Recruit AhR E3 Ligase to Target Proteins (Wed, 16 Oct 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00704
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[ASAP] Immunological Evaluation of Synthetic Glycosylphosphatidylinositol Glycoconjugates as Vaccine Candidates against Malaria (Tue, 15 Oct 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00739
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[ASAP] Development of a Chemical Toolset for Studying the Paralog-Specific Function of IRE1 (Mon, 14 Oct 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00482
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[ASAP] Inhibiting <italic toggle="yes">Mycobacterium tuberculosis</italic> DosRST Signaling by Targeting Response Regulator DNA Binding and Sensor Kinase Heme (Mon, 14 Oct 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.8b00849
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[ASAP] Click-Particle Display for Base-Modified Aptamer Discovery (Sat, 12 Oct 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00587
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