ACS Chemical Biology

Rational Redesign of a Functional Protein Kinase-Substrate Interaction (Wed, 29 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00089
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Recruitment and Regulation of the Non-ribosomal Peptide Synthetase Modifying Cytochrome P450 Involved in Nikkomycin Biosynthesis (Tue, 28 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00081
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The Macrolide Toxin Mycolactone Promotes Bim-Dependent Apoptosis in Buruli Ulcer through Inhibition of mTOR (Mon, 27 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00053
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Histo-Blood Group Antigen Presentation Is Critical for Binding of Norovirus VLP to Glycosphingolipids in Model Membranes (Mon, 27 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00152
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Tracing Effects of Fluorine Substitutions on G-Quadruplex Conformational Changes (Mon, 27 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01096
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Stepwise Loop Insertion Strategy for Active Site Remodeling to Generate Novel Enzyme Functions (Mon, 27 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00018
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An Unusual Flavin-Dependent Halogenase from the Metagenome of the Marine Sponge Theonella swinhoei WA (Fri, 24 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01115
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New Ulvan-Degrading Polysaccharide Lyase Family: Structure and Catalytic Mechanism Suggests Convergent Evolution of Active Site Architecture (Thu, 23 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00126
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Selective Downregulation of JAK2 and JAK3 by an ATP-Competitive pan-JAK Inhibitor (Wed, 22 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00116
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Novel Peptides Derived from Dengue Virus Capsid Protein Translocate Reversibly the Blood–Brain Barrier through a Receptor-Free Mechanism (Tue, 21 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00087
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A Chemical Probe Strategy for Interrogating Inhibitor Selectivity Across the MEK Kinase Family (Mon, 20 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01060
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Proteolysis-Targeting Chimeras: Induced Protein Degradation as a Therapeutic Strategy (Mon, 20 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01068
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Meeting Proceedings ICBS2016Translating the Power of Chemical Biology to Clinical Advances (Fri, 17 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00205
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Mechanism-Based Inhibition of the Mycobacterium tuberculosis Branched-Chain Aminotransferase by d- and l-Cycloserine (Thu, 16 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00142
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Discovery of an Extended Austinoid Biosynthetic Pathway in Aspergillus calidoustus (Wed, 15 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00003
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Glycation of Lysozyme by Glycolaldehyde Provides New Mechanistic Insights in Diabetes-Related Protein Aggregation (Tue, 14 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01103
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Biased Signaling by Agonists of Protease Activated Receptor 2 (Tue, 14 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01088
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Structure–Activity Relationships of the Competence Stimulating Peptides (CSPs) in Streptococcus pneumoniae Reveal Motifs Critical for Intra-group and Cross-group ComD Receptor Activation (Fri, 10 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00007
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A Fluorescent Probe Distinguishes between Inhibition of Early and Late Steps of Lipopolysaccharide Biogenesis in Whole Cells (Thu, 09 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00159
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Mapping Novel Metabolic Nodes Targeted by Anti-Cancer Drugs that Impair Triple-Negative Breast Cancer Pathogenicity (Wed, 08 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01159
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A Near-Infrared, Wavelength-Shiftable, Turn-on Fluorescent Probe for the Detection and Imaging of Cancer Tumor Cells (Tue, 07 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01094
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Ion Mobility-Mass Spectrometry Reveals a Dipeptide That Acts as a Molecular Chaperone for Amyloid β (Mon, 06 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00045
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The Role of the Secondary Coordination Sphere in a Fungal Polysaccharide Monooxygenase (Fri, 03 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00016
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Lysine-Tryptophan-Crosslinked Peptides Produced by Radical SAM Enzymes in Pathogenic Streptococci (Fri, 03 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01069
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NMR and Molecular Recognition of N-Glycans: Remote Modifications of the Saccharide Chain Modulate Binding Features (Fri, 03 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01116
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Mitochondrial Cysteine Desulfurase and ISD11 Coexpressed in Escherichia coli Yield Complex Containing Acyl Carrier Protein (Thu, 02 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01005
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Fluorescent Hexose Conjugates Establish Stringent Stereochemical Requirement by GLUT5 for Recognition and Transport of Monosaccharides (Thu, 02 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01101
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Discovery and Characterization of a Potent and Specific Peptide Ligand Targeting Endothelial Progenitor Cells and Endothelial Cells for Tissue Regeneration (Thu, 02 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00118
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The GCaMP-R Family of Genetically Encoded Ratiometric Calcium Indicators (Wed, 01 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b00883
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Argininosuccinate Synthase 1 is a Metabolic Regulator of Colorectal Cancer Pathogenicity (Wed, 01 Mar 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01158
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A Fluorescent Hsp90 Probe Demonstrates the Unique Association between Extracellular Hsp90 and Malignancy in Vivo (Thu, 23 Feb 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00006
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Iron Release from the Siderophore Pyoverdine in Pseudomonas aeruginosa Involves Three New Actors: FpvC, FpvG, and FpvH (Thu, 23 Feb 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01077
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Highly Potent Cell-Permeable and Impermeable NanoLuc Luciferase Inhibitors (Wed, 22 Feb 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01129
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O-GlcNAcylation of α-Synuclein at Serine 87 Reduces Aggregation without Affecting Membrane Binding (Wed, 22 Feb 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00113
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Eg5 Inhibitors Have Contrasting Effects on Microtubule Stability and Metaphase Spindle Integrity (Wed, 22 Feb 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01040
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Mechanistic Debris Generated by Twister Ribozymes (Tue, 21 Feb 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00010
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The Activity of JmjC Histone Lysine Demethylase KDM4A is Highly Sensitive to Oxygen Concentrations (Mon, 20 Feb 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b00958
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Evolution and Distribution of C7–Cyclitol Synthases in Prokaryotes and Eukaryotes (Fri, 17 Feb 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00066
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Control of an Unusual Photo-Claisen Rearrangement in Coumarin Caged Tamoxifen through an Extended Spacer (Fri, 17 Feb 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b00999
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Determinants of BH3 Sequence Specificity for the Disruption of Bcl-xL/cBid Complexes in Membranes (Fri, 17 Feb 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01084
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Modification of the Orthosteric PPARγ Covalent Antagonist Scaffold Yields an Improved Dual-Site Allosteric Inhibitor (Thu, 16 Feb 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01015
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Characterization of CYP115 As a Gibberellin 3-Oxidase Indicates That Certain Rhizobia Can Produce Bioactive Gibberellin A4 (Thu, 16 Feb 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01038
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The SUV39H1 Protein Lysine Methyltransferase Methylates Chromatin Proteins Involved in Heterochromatin Formation and VDJ Recombination (Thu, 16 Feb 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01076
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Identifying Functional Cysteine Residues in the Mitochondria (Wed, 15 Feb 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01074
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Chemoproteomic Screening of Covalent Ligands Reveals UBA5 As a Novel Pancreatic Cancer Target (Wed, 15 Feb 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00020
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Structural and Epimeric Isomers of HPPH [3-Devinyl 3-{1-(1-hexyloxy) ethyl}pyropheophorbide-a]: Effects on Uptake and Photodynamic Therapy of Cancer (Wed, 15 Feb 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00023
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Chemically-Modified Peptides Targeting the PDZ Domain of GIPC as a Therapeutic Approach for Cancer (Tue, 10 Mar 2015)
ACS Chemical Biology DOI: 10.1021/cb500865a
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