ACS Chemical Biology

Celiac Disease: Lessons for and from Chemical Biology (Mon, 22 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01155
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Stabilization of Glucocerebrosidase by Active Site Occupancy (Mon, 22 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00276
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Hidden Antioxidative Functions of Reduced Nicotinamide Adenine Dinucleotide Coexisting with Hemoglobin (Fri, 19 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00174
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N-Phenylacetylation and Nonribosomal Peptide Synthetases with Substrate Promiscuity for Biosynthesis of Heptapeptide Variants, JBIR-78 and JBIR-95 (Fri, 19 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00314
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Heterologous Production and Yield Improvement of Epothilones in Burkholderiales Strain DSM 7029 (Thu, 18 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00097
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The N6-Position of Adenine Is a Blind Spot for TAL-Effectors That Enables Effective Binding of Methylated and Fluorophore-Labeled DNA (Wed, 17 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00324
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Efficient Inhibition of SmNACE by Coordination Complexes Is Abolished by S. mansoni Sequestration of Metal (Wed, 17 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00186
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Rearranged Biosynthetic Gene Cluster and Synthesis of Hassallidin E in Planktothrix serta PCC 8927 (Wed, 17 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00093
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Real-Time Imaging of the Azole Class of Antifungal Drugs in Live Candida Cells (Fri, 12 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00339
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Iron Uptake Oxidoreductase (IruO) Uses a Flavin Adenine Dinucleotide Semiquinone Intermediate for Iron-Siderophore Reduction (Fri, 12 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00203
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Discovery and Characterization of a Eukaryotic Initiation Factor 4A-3-Selective Inhibitor That Suppresses Nonsense-Mediated mRNA Decay (Wed, 10 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00041
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Phanerochaete chrysosporium Multienzyme Catabolic System for in Vivo Modification of Synthetic Lignin to Succinic Acid (Wed, 10 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00046
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Citrullination/Methylation Crosstalk on Histone H3 Regulates ER-Target Gene Transcription (Tue, 09 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00241
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Phosphorylation Weakens but Does Not Inhibit Membrane Binding and Clustering of K-Ras4B (Tue, 09 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00165
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Nickel(II) Inhibits Tet-Mediated 5-Methylcytosine Oxidation by High Affinity Displacement of the Cofactor Iron(II) (Mon, 08 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00261
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A Chemical-Genetic Approach to Generate Selective Covalent Inhibitors of Protein Kinases (Mon, 08 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01083
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The Folding Pathway of the KIX Domain (Mon, 08 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00289
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HIV-1 Frameshift RNA-Targeted Triazoles Inhibit Propagation of Replication-Competent and Multi-Drug-Resistant HIV in Human Cells (Fri, 05 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00052
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Glycan Remodeling of Human Erythropoietin (EPO) Through Combined Mammalian Cell Engineering and Chemoenzymatic Transglycosylation (Fri, 05 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00282
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Comparison of the Deacylase and Deacetylase Activity of Zinc-Dependent HDACs (Thu, 04 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00321
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Understanding Carbapenem Translocation through OccD3 (OpdP) of Pseudomonas aeruginosa (Thu, 04 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01150
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Biosynthetic Insights into Linaridin Natural Products from Genome Mining and Precursor Peptide Mutagenesis (Wed, 03 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00262
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CRISPR–Cas9 Mediated DNA Unwinding Detected Using Site-Directed Spin Labeling (Wed, 03 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b01137
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Heavy Metals Induce Decline of Derivatives of 5-Methycytosine in Both DNA and RNA of Stem Cells (Wed, 03 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00170
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Structural Insights into the CotB2-Catalyzed Cyclization of Geranylgeranyl Diphosphate to the Diterpene Cyclooctat-9-en-7-ol (Tue, 02 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00154
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High-Efficiency “–1” and “–2” Ribosomal Frameshiftings Revealed by Force Spectroscopy (Tue, 02 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00028
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A Macrocyclic Peptide Ligand Binds the Oncogenic MicroRNA-21 Precursor and Suppresses Dicer Processing (Tue, 02 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00180
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Unified Biosynthetic Origin of the Benzodipyrrole Subunits in CC-1065 (Tue, 02 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00302
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The A-Rule and Deletion Formation During Abasic and Oxidized Abasic Site Bypass by DNA Polymerase θ (Mon, 01 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00211
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Polypharmacological in Silico Bioactivity Profiling and Experimental Validation Uncovers Sedative-Hypnotic Effects of Approved and Experimental Drugs in Rat (Mon, 01 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00209
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Synergistic Effects of an Irreversible DNA Polymerase Inhibitor and DNA Damaging Agents on HeLa Cells (Mon, 01 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00259
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NHS-Esters As Versatile Reactivity-Based Probes for Mapping Proteome-Wide Ligandable Hotspots (Mon, 01 May 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00125
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Systematic Synthesis and Binding Study of HIV V3 Glycopeptides Reveal the Fine Epitopes of Several Broadly Neutralizing Antibodies (Fri, 28 Apr 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00319
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Discovery of the Showdomycin Gene Cluster from Streptomyces showdoensis ATCC 15227 Yields Insight into the Biosynthetic Logic of C-Nucleoside Antibiotics (Thu, 27 Apr 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00078
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Substrate Profiling and High Resolution Co-complex Crystal Structure of a Secreted C11 Protease Conserved across Commensal Bacteria (Thu, 27 Apr 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00143
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Phylogenomic Analysis of the Microviridin Biosynthetic Pathway Coupled with Targeted Chemo-Enzymatic Synthesis Yields Potent Protease Inhibitors (Wed, 26 Apr 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00124
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Profiling Cellular Substrates of Lysine Acetyltransferases GCN5 and p300 with Orthogonal Labeling and Click Chemistry (Wed, 26 Apr 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00114
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Disclosing the Interaction of Carbonic Anhydrase IX with Cullin-Associated NEDD8-Dissociated Protein 1 by Molecular Modeling and Integrated Binding Measurements (Wed, 19 Apr 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00055
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New Acridine Thiourea Gold(I) Anticancer Agents: Targeting the Nucleus and Inhibiting Vasculogenic Mimicry (Wed, 19 Apr 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00090
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The Root Growth-Regulating Brevicompanine Natural Products Modulate the Plant Circadian Clock (Wed, 19 Apr 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.6b00978
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Nature’s Selection of Geranyl Group as a tRNA Modification: The Effects of Chain Length on Base-Pairing Specificity (Tue, 18 Apr 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00108
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Structural Study on the Reaction Mechanism of a Free Serine Kinase Involved in Cysteine Biosynthesis (Tue, 18 Apr 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00064
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Chemically-Modified Peptides Targeting the PDZ Domain of GIPC as a Therapeutic Approach for Cancer (Tue, 10 Mar 2015)
ACS Chemical Biology DOI: 10.1021/cb500865a
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