ACS Chemical Biology



[ASAP] L,D-Transpeptidase Specific Probe Reveals Spatial Activity of Peptidoglycan Cross-Linking (Mon, 16 Sep 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00427
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[ASAP] Vancomycin–Arginine Conjugate Inhibits Growth of Carbapenem-Resistant <italic toggle="yes">E. coli</italic> and Targets Cell-Wall Synthesis (Thu, 12 Sep 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00565
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[ASAP] Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine (Wed, 11 Sep 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00367
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[ASAP] Metabolic Pathway Rerouting in <italic toggle="yes">Paraburkholderia rhizoxinica</italic> Evolved Long-Overlooked Derivatives of Coenzyme F<sub>420</sub> (Wed, 11 Sep 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00605
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[ASAP] Leveraging Peptide Substrate Libraries to Design Inhibitors of Bacterial Lon Protease (Tue, 10 Sep 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00529
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[ASAP] A Biased Agonist at Immunometabolic Receptor GPR84 Causes Distinct Functional Effects in Macrophages (Tue, 10 Sep 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00533
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[ASAP] Abscisic Acid Derivatives with Different Alkyl Chain Lengths Activate Distinct Abscisic Acid Receptor Subfamilies (Mon, 09 Sep 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00453
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[ASAP] Reconstitution and Substrate Specificity of the Thioether-Forming Radical <italic toggle="yes">S</italic>-Adenosylmethionine Enzyme in Freyrasin Biosynthesis (Mon, 09 Sep 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00457
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[ASAP] GTP-Dependent Formation of Multimeric G-Quadruplexes (Thu, 05 Sep 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00428
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[ASAP] Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader (Thu, 05 Sep 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00505
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[ASAP] Direct Evidence of an Enzyme-Generated LPP Intermediate in (+)-Limonene Synthase Using a Fluorinated GPP Substrate Analog (Wed, 04 Sep 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00514
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[ASAP] SIRT2 and Lysine Fatty Acylation Regulate the Activity of RalB and Cell Migration (Tue, 03 Sep 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00492
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[ASAP] Directed Evolution Reveals the Functional Sequence Space of an Adenylation Domain Specificity Code (Tue, 03 Sep 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00532
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[ASAP] Evaluation of Chemically-Cleavable Linkers for Quantitative Mapping of Small Molecule-Cysteinome Reactivity (Thu, 29 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00424
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[ASAP] Leveraging Atropisomerism to Obtain a Selective Inhibitor of RET Kinase with Secondary Activities toward EGFR Mutants (Thu, 29 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00407
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[ASAP] Small Molecule Targeting TDP-43’s RNA Recognition Motifs Reduces Locomotor Defects in a <italic toggle="yes">Drosophila</italic> Model of Amyotrophic Lateral Sclerosis (ALS) (Tue, 27 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00481
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[ASAP] Differential Recognition of Deacetylated PNAG Oligosaccharides by a Biofilm Degrading Glycosidase (Tue, 27 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00467
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[ASAP] Identification of Novel a-Pyrones from <italic toggle="yes">Conexibacter woesei</italic> Serving as Sulfate Shuttles (Tue, 27 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00455
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[ASAP] Nutrient-Based Chemical Library as a Source of Energy Metabolism Modulators (Mon, 26 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00444
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[ASAP] Ex Vivo Analysis of Tryptophan Metabolism Using <sup>19</sup>F NMR (Mon, 26 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00548
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[ASAP] N-Terminomics/TAILS Profiling of Proteases and Their Substrates in Ulcerative Colitis (Wed, 21 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00608
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[ASAP] Sulfonamide-Based Inhibitors of Biotin Protein Ligase as New Antibiotic Leads (Wed, 21 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00463
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[ASAP] Fully Synthetic Heparan Sulfate-Based Neural Tissue Construct That Maintains the Undifferentiated State of Neural Stem Cells (Wed, 21 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00401
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[ASAP] Structural Basis of Glycerophosphodiester Recognition by the <italic toggle="yes">Mycobacterium tuberculosis</italic> Substrate-Binding Protein UgpB (Wed, 21 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00204
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[ASAP] Cell Membrane Composition Drives Selectivity and Toxicity of Designed Cyclic Helix–Loop–Helix Peptides with Cell Penetrating and Tumor Suppressor Properties (Wed, 21 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00593
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[ASAP] Structure-Based Mutagenesis of Phycobiliprotein smURFP for Optoacoustic Imaging (Tue, 20 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00299
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[ASAP] CETSA beyond Soluble Targets: a Broad Application to Multipass Transmembrane Proteins (Fri, 16 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00399
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[ASAP] Protease Substrate Identification Using N-terminomics (Thu, 15 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00398
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[ASAP] <italic toggle="yes">In Vitro</italic> Characterization of the Colibactin-Activating Peptidase ClbP Enables Design of a Fluorogenic Activity Probe (Wed, 14 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00540
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[ASAP] Development of a Cyclic Peptide Inhibitor of the p6/UEV Protein–Protein Interaction (Wed, 14 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00627
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[ASAP] Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance (Tue, 13 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00370
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[ASAP] Rapid Screen for Tyrosine Kinase Inhibitor Resistance Mutations and Substrate Specificity (Thu, 08 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00283
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[ASAP] Chemical Tools and Biochemical Assays for SUMO Specific Proteases (SENPs) (Mon, 05 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00402
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[ASAP] Selective and Rapid Cell-Permeable Inhibitor of Human Caspase-3 (Thu, 01 Aug 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00564
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[ASAP] Discovery of Cellular Roles of Intramembrane Proteases (Wed, 24 Jul 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00404
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[ASAP] Procaspase-3 Overexpression in Cancer: A Paradoxical Observation with Therapeutic Potential (Tue, 16 Jul 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00338
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[ASAP] Chemical Modulation of Human Mitochondrial ClpP: Potential Application in Cancer Therapeutics (Wed, 10 Jul 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00347
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[ASAP] Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications (Mon, 13 May 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.8b01083
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[ASAP] Chemically-Modified Peptides Targeting the PDZ Domain of GIPC as a Therapeutic Approach for Cancer (Tue, 10 Mar 2015)
TOC Graphic ACS Chemical Biology DOI: 10.1021/cb500865a
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