ACS Chemical Biology

Oxidatively Generated Lesions as Internal Photosensitizers for Pyrimidine Dimerization in DNA (Wed, 17 Jan 2018)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b01097
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Investigation of Amide Bond Formation during Dehydrophos Biosynthesis (Fri, 12 Jan 2018)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00949
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Generation of Optogenetically Modified Adenovirus Vector for Spatiotemporally Controllable Gene Therapy (Fri, 12 Jan 2018)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b01058
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Live Cell Visualization of Multiple Protein–Protein Interactions with BiFC Rainbow (Thu, 11 Jan 2018)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00931
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Time-Resolved Tracking of Separately Internalized Neuropeptide Y2 Receptors by Two-Color Pulse-Chase (Thu, 11 Jan 2018)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00999
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Development of Stabilized Peptide-Based PROTACs against Estrogen Receptor α (Thu, 11 Jan 2018)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00985
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Identifying Novel Enhancer Elements with CRISPR-Based Screens (Wed, 10 Jan 2018)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00778
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A Single Amide Linkage in the Passenger Strand Suppresses Its Activity and Enhances Guide Strand Targeting of siRNAs (Wed, 10 Jan 2018)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b01012
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Discovery of a 29-Amino-Acid Reactive Abiotic Peptide for Selective Cysteine Arylation (Tue, 09 Jan 2018)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00520
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Rational-Differential Design of Highly Specific Glycomimetic Ligands: Targeting DC-SIGN and Excluding Langerin Recognition (Mon, 08 Jan 2018)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00958
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Multiple Chemical Inducible Tal Effectors for Genome Editing and Transcription Activation (Mon, 08 Jan 2018)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00606
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Next-Generation DNA-Functionalized Quantum Dots as Biological Sensors (Thu, 04 Jan 2018)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00887
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Structural Basis of ALDH1A2 Inhibition by Irreversible and Reversible Small Molecule Inhibitors (Wed, 03 Jan 2018)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00685
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Comparison of the Response of Bacterial IscU and SufU to Zn2+ and Select Transition-Metal Ions (Wed, 03 Jan 2018)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00442
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Structure-Based Identification of HIV-1 Nucleocapsid Protein Inhibitors Active against Wild-Type and Drug-Resistant HIV-1 Strains (Thu, 28 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00907
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The Future of Multiplexed Eukaryotic Genome Engineering (Thu, 28 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00842
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Correction to Global Awakening of Cryptic Biosynthetic Gene Clusters in Burkholderia thailandensis (Thu, 28 Dec 2017)
ACS Chemical Biology DOI: 10.1021/acschembio.7b01056
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Homospermidine Lipids: A Compound Class Specifically Formed during Fruiting Body Formation of Myxococcus xanthus DK1622 (Thu, 28 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00816
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CrocadepsinsDepsipeptides from the Myxobacterium Chondromyces crocatus Found by a Genome Mining Approach (Thu, 28 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00900
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Discovering the Genome-Wide Activity of CRISPR-Cas Nucleases (Wed, 27 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00847
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Mining Plants for Bacterial Quorum Sensing Modulators (Wed, 27 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00859
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Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017Utility and Limitations (Tue, 26 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00903
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Small Molecule Chelators Reveal That Iron Starvation Inhibits Late Stages of Bacterial Cytokinesis (Wed, 20 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00560
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Type II-C CRISPR-Cas9 Biology, Mechanism, and Application (Wed, 20 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00855
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Modulating DNA Repair Pathways to Improve Precision Genome Engineering (Wed, 20 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00777
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Determinants and Prediction of Esterase Substrate Promiscuity Patterns (Wed, 20 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00996
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Expanding the Bioactive Chemical Space of Anthrabenzoxocinones through Engineering the Highly Promiscuous Biosynthetic Modification Steps (Tue, 19 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00743
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Direct Substrate Identification with an Analog Sensitive (AS) Viral Cyclin-Dependent Kinase (v-Cdk) (Tue, 19 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00972
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Retraction of “The L3MBTL3 Methyl-Lysine Reader Domain Functions As a Dimer” (Tue, 19 Dec 2017)
ACS Chemical Biology DOI: 10.1021/acschembio.7b01061
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Site-Selective RNA Splicing Nanozyme: DNAzyme and RtcB Conjugates on a Gold Nanoparticle (Tue, 19 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00437
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Mode of Action and Heterologous Expression of the Natural Product Antibiotic Vancoresmycin (Tue, 19 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00733
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Identification and Experimental Characterization of an Extremophilic Brine Pool Alcohol Dehydrogenase from Single Amplified Genomes (Mon, 18 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00792
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Myricetin Reduces Toxic Level of CAG Repeats RNA in Huntington’s Disease (HD) and Spino Cerebellar Ataxia (SCAs) (Mon, 18 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00699
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NRPS-Derived Isoquinolines and Lipopetides Mediate Antagonism between Plant Pathogenic Fungi and Bacteria (Mon, 18 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00731
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Reaction-Based Fluorescent Probes for the Imaging of Nitroxyl (HNO) in Biological Systems (Fri, 15 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00901
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Innovations in Undergraduate Chemical Biology Education (Thu, 14 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00986
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Synthesis of bis-Phosphate Iminoaltritol Enantiomers and Structural Characterization with Adenine Phosphoribosyltransferase (Thu, 14 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00601
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Development of a Protease Biosensor Based on a Dimerization-Dependent Red Fluorescent Protein (Tue, 12 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00715
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Conformational Dynamics of DNA Binding and Cas3 Recruitment by the CRISPR RNA-Guided Cascade Complex (Tue, 12 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00649
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The Molecular Mechanism of Substrate Recognition and Catalysis of the Membrane Acyltransferase PatA from Mycobacteria (Mon, 11 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00578
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The Thioesterase Domain in Glycopeptide Antibiotic Biosynthesis Is Selective for Cross-Linked Aglycones (Mon, 11 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00943
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Polymyxin-Induced Lipid A Deacylation in Pseudomonas aeruginosa Perturbs Polymyxin Penetration and Confers High-Level Resistance (Mon, 11 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00836
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Structural and Functional Studies of the Daunorubicin Priming Ketosynthase DpsC (Mon, 11 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00551
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New Structural Insights into Formation of the Key Actin Regulating WIP-WASp Complex Determined by NMR and Molecular Imaging (Thu, 07 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00486
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Design of Plasmodium vivax Hypoxanthine-Guanine Phosphoribosyltransferase Inhibitors as Potential Antimalarial Therapeutics (Tue, 05 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00916
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Apratyramide, a Marine-Derived Peptidic Stimulator of VEGF-A and Other Growth Factors with Potential Application in Wound Healing (Tue, 05 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00827
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Diverse Class 2 CRISPR-Cas Effector Proteins for Genome Engineering Applications (Tue, 05 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00800
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ToP-DNJ, a Selective Inhibitor of Endoplasmic Reticulum α-Glucosidase II Exhibiting Antiflaviviral Activity (Tue, 05 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00870
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Advances in the Chemical Biology of Desferrioxamine B (Mon, 04 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00851
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Design and Application of a DNA-Encoded Macrocyclic Peptide Library (Mon, 04 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00852
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Chemical Proteomics Reveals Soluble Epoxide Hydrolase as a Therapeutic Target for Ocular Neovascularization (Fri, 01 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00854
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Chemically Precise Glycoengineering Improves Human Insulin (Fri, 01 Dec 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00794
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Fluorescent Probes of DNA Repair (Thu, 30 Nov 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00919
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Repair of a Site-Specific DNA Cleavage: Old-School Lessons for Cas9-Mediated Gene Editing (Tue, 14 Nov 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00760
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Tuning the Color Palette of Fluorescent Copper Sensors through Systematic Heteroatom Substitution at Rhodol Cores (Tue, 07 Nov 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00748
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CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine (Tue, 24 Oct 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00657
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The Promise and Challenge of In Vivo Delivery for Genome Therapeutics (Thu, 19 Oct 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00680
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Genome Editing: Insights from Chemical Biology to Support Safe and Transformative Therapeutic Applications (Wed, 18 Oct 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00689
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Editing the Genome Without Double-Stranded DNA Breaks (Mon, 09 Oct 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00710
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Two-Color 810 nm STED Nanoscopy of Living Cells with Endogenous SNAP-Tagged Fusion Proteins (Mon, 02 Oct 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00616
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A Single-Chain Photoswitchable CRISPR-Cas9 Architecture for Light-Inducible Gene Editing and Transcription (Fri, 29 Sep 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00603
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Discovery of Oligonucleotide Signaling Mediated by CRISPR-Associated Polymerases Solves Two Puzzles but Leaves an Enigma (Wed, 27 Sep 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00713
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CRISPR-Mediated Tagging of Endogenous Proteins with a Luminescent Peptide (Thu, 21 Sep 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00549
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Rheostatic Control of Cas9-Mediated DNA Double Strand Break (DSB) Generation and Genome Editing (Fri, 15 Sep 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00652
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Multidimensional Control of Cas9 by Evolved RNA Polymerase-Based Biosensors (Tue, 22 Aug 2017)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.7b00532
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Chemically-Modified Peptides Targeting the PDZ Domain of GIPC as a Therapeutic Approach for Cancer (Tue, 10 Mar 2015)
ACS Chemical Biology DOI: 10.1021/cb500865a
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