ACS Chemical Biology



[ASAP] Small-Molecule Antagonists of the RIG-I Innate Immune Receptor (Mon, 27 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00810
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[ASAP] Discovery of Novel Latency-Associated Nuclear Antigen Inhibitors as Antiviral Agents Against Kaposi’s Sarcoma-Associated Herpesvirus (Fri, 24 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00845
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[ASAP] HaloTag-Based Hybrid Targetable and Ratiometric Sensors for Intracellular Zinc (Fri, 24 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00872
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[ASAP] Integrative X-ray Structure and Molecular Modeling for the Rationalization of Procaspase-8 Inhibitor Potency and Selectivity (Thu, 23 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.0c00019
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[ASAP] An Inactive Dispersin B Probe for Monitoring PNAG Production in Biofilm Formation (Tue, 21 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00907
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[ASAP] Profiling Cysteine Reactivity and Oxidation in the Endoplasmic Reticulum (Wed, 15 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b01014
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[ASAP] Small Molecule Inhibitor Screen Reveals Calcium Channel Signaling as a Mechanistic Mediator of <italic toggle="yes">Clostridium difficile</italic> TcdB-Induced Necrosis (Tue, 14 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00906
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[ASAP] Metallointercalator [Ru(dppz)<sub>2</sub>(PIP)]<sup>2+</sup> Renders BRCA Wild-Type Triple-Negative Breast Cancer Cells Hypersensitive to PARP Inhibition (Tue, 14 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00843
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[ASAP] The Chemical Synthesis, Stability, and Activity of MAIT Cell Prodrug Agonists That Access MR1 in Recycling Endosomes (Tue, 14 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00902
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[ASAP] Radiation-Induced Lipid Peroxidation Triggers Ferroptosis and Synergizes with Ferroptosis Inducers (Tue, 14 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00939
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[ASAP] Chemical Mechanisms of Colonization Resistance by the Gut Microbial Metabolome (Tue, 14 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00813
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[ASAP] Site-Specific Siderocalin Binding to Ferric and Ferric-Free Enterobactin As Revealed by Mass Spectrometry (Mon, 13 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00741
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[ASAP] Structure-Specific Cleavage of an RNA Repeat Expansion with a Dimeric Small Molecule Is Advantageous over Sequence-Specific Recognition by an Oligonucleotide (Mon, 13 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00958
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[ASAP] Heat-Triggered Remote Control of CRISPR-dCas9 for Tunable Transcriptional Modulation (Mon, 13 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b01005
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[ASAP] Discovery of PqsE Thioesterase Inhibitors for <italic toggle="yes">Pseudomonas aeruginosa</italic> Using DNA-Encoded Small Molecule Library Screening (Fri, 10 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00905
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[ASAP] Discovery of a Small Molecule Probe of Rpn-6, an Essential Subunit of the 26S Proteasome (Fri, 10 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b01019
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[ASAP] Discovery of the Biosynthetic Machinery for Stravidins, Biotin Antimetabolites (Thu, 09 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00890
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[ASAP] An Immune-Stimulatory Helix–Loop–Helix Peptide: Selective Inhibition of CTLA-4–B7 Interaction (Wed, 08 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00743
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[ASAP] Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases (Wed, 08 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00887
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[ASAP] Molecular and Structural Mechanism of Pan-Genotypic HCV NS3/4A Protease Inhibition by Glecaprevir (Wed, 08 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00675
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[ASAP] Thailandenes, Cryptic Polyene Natural Products Isolated from <italic toggle="yes">Burkholderia thailandensis</italic> Using Phenotype-Guided Transposon Mutagenesis (Thu, 02 Jan 2020)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00883
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[ASAP] Genome Mining and Heterologous Expression Reveal Two Distinct Families of Lasso Peptides Highly Conserved in Endofungal Bacteria (Wed, 18 Dec 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00805
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[ASAP] Heterologous Biosynthesis of Type II Polyketide Products Using <italic toggle="yes">E. coli</italic> (Mon, 16 Dec 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00827
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[ASAP] End-Binding E3 Ubiquitin Ligases Enable Protease Signaling (Wed, 20 Nov 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00621
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[ASAP] Identification and Mobilization of a Cryptic Antibiotic Biosynthesis Gene Locus from a Human-Pathogenic <italic toggle="yes">Nocardia</italic> Isolate (Thu, 14 Nov 2019)
TOC Graphic ACS Chemical Biology DOI: 10.1021/acschembio.9b00763
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