ACS Medicinal Chemistry Letters

Discovery of a Series of Indazole TRPA1 Antagonists (Mon, 22 May 2017)
TOC Graphic ACS Medicinal Chemistry Letters DOI: 10.1021/acsmedchemlett.7b00140
>> Read More

Photoaffinity Labeling of the Human A2A Adenosine Receptor and Cross-link Position Analysis by Mass Spectrometry (Mon, 22 May 2017)
TOC Graphic ACS Medicinal Chemistry Letters DOI: 10.1021/acsmedchemlett.7b00138
>> Read More

JAK2 JH2 Fluorescence Polarization Assay and Crystal Structures for Complexes with Three Small Molecules (Mon, 22 May 2017)
TOC Graphic ACS Medicinal Chemistry Letters DOI: 10.1021/acsmedchemlett.7b00154
>> Read More

Identification and Characterization of JAK2 Pseudokinase Domain Small Molecule Binders (Mon, 22 May 2017)
TOC Graphic ACS Medicinal Chemistry Letters DOI: 10.1021/acsmedchemlett.7b00153
>> Read More

Where Are Drugs Invented, and Why Does It Matter? (Tue, 16 May 2017)
ACS Medicinal Chemistry Letters DOI: 10.1021/acsmedchemlett.7b00185
>> Read More

Discovery of Potent and Selective Tricyclic Inhibitors of Bruton’s Tyrosine Kinase with Improved Druglike Properties (Tue, 16 May 2017)
TOC Graphic ACS Medicinal Chemistry Letters DOI: 10.1021/acsmedchemlett.7b00103
>> Read More

Study of para-Quinone Methide Precursors toward the Realkylation of Aged Acetylcholinesterase (Tue, 16 May 2017)
TOC Graphic ACS Medicinal Chemistry Letters DOI: 10.1021/acsmedchemlett.7b00037
>> Read More

Crystal Structure of a Human K-Ras G12D Mutant in Complex with GDP and the Cyclic Inhibitory Peptide KRpep-2d (Mon, 15 May 2017)
TOC Graphic ACS Medicinal Chemistry Letters DOI: 10.1021/acsmedchemlett.7b00128
>> Read More

Identification of Better Pharmacokinetic Benzothiazinone Derivatives as New Antitubercular Agents (Fri, 12 May 2017)
TOC Graphic ACS Medicinal Chemistry Letters DOI: 10.1021/acsmedchemlett.7b00106
>> Read More

Antiobesity Effect of a Short-Length Peptide YY Analogue after Continuous Administration in Mice (Wed, 10 May 2017)
TOC Graphic ACS Medicinal Chemistry Letters DOI: 10.1021/acsmedchemlett.7b00047
>> Read More

Efficient Divergent Synthesis of New Immunostimulant 4″-Modified α-Galactosylceramide Analogues (Tue, 09 May 2017)
TOC Graphic ACS Medicinal Chemistry Letters DOI: 10.1021/acsmedchemlett.7b00107
>> Read More

Systematic Data Mining Reveals Synergistic H3R/MCHR1 Ligands (Mon, 08 May 2017)
TOC Graphic ACS Medicinal Chemistry Letters DOI: 10.1021/acsmedchemlett.7b00118
>> Read More

Saccharin Aza BioisosteresSynthesis and Preclinical Property Comparisons (Mon, 08 May 2017)
TOC Graphic ACS Medicinal Chemistry Letters DOI: 10.1021/acsmedchemlett.7b00137
>> Read More

Synthesis and Evaluation of a Linkable Functional Group-Equipped Analogue of the Epothilones (Thu, 04 May 2017)
TOC Graphic ACS Medicinal Chemistry Letters DOI: 10.1021/acsmedchemlett.7b00131
>> Read More

Development of Quinazoline/Pyrimidine-2,4(1H,3H)-diones as Agonists of Cannabinoid Receptor Type 2 (Wed, 03 May 2017)
TOC Graphic ACS Medicinal Chemistry Letters DOI: 10.1021/acsmedchemlett.7b00007
>> Read More

Synthesis and Anti-HCV Activity of a Novel 2′,3′-Dideoxy-2′-α-fluoro-2′-β-C-methyl Guanosine Phosphoramidate Prodrug (Wed, 03 May 2017)
TOC Graphic ACS Medicinal Chemistry Letters DOI: 10.1021/acsmedchemlett.7b00174
>> Read More

Exploitation of Conformational Dynamics in Imparting Selective Inhibition for Related Matrix Metalloproteinases (Wed, 03 May 2017)
TOC Graphic ACS Medicinal Chemistry Letters DOI: 10.1021/acsmedchemlett.7b00130
>> Read More

19F-NMR-Based Dual-Site Reporter Assay for the Discovery and Distinction of Catalytic and Allosteric Kinase Inhibitors (Thu, 06 Apr 2017)
TOC Graphic ACS Medicinal Chemistry Letters DOI: 10.1021/acsmedchemlett.7b00084
>> Read More

Site Search