ChemMedChem



Bicyclic imidazolium inhibitors of Gli transcription factor activity ()
ChemMedChem, Accepted Article.
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Multitarget compounds for bipolar disorder: from rational design to preliminary pharmacokinetic evaluation ()
ChemMedChem, Accepted Article.
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N‐Substituted Nipecotic Acids as (S)‐SNAP‐5114 Analogues with Modified Lipophilic Domains ()
ChemMedChem, EarlyView.
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Structure‐Based Design of FXIIIa‐Blockers: Addressing a Transient Hydrophobic Pocket in the Active Site of FXIIIa ()
ChemMedChem, EarlyView.
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Synthesis and Biological Evaluation of Hapten‐Clicked Analogues of The Antigenic Peptide Melan‐A/MART‐126(27L)‐35 ()
ChemMedChem, EarlyView.
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Early Drug‐Discovery Efforts towards the Identification of EP300/CBP Histone Acetyltransferase (HAT) Inhibitors ()
ChemMedChem, EarlyView.
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Novel, Dual Target‐Directed Annelated Xanthine Derivatives Acting on Adenosine Receptors and Monoamine Oxidase B ()
ChemMedChem, EarlyView.
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Structure activity relationship of phenylpyrazolones against Trypanosoma cruzi ()
ChemMedChem, Accepted Article.
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Solid‐Phase Multicomponent Synthesis of 3‐Substituted Isoindolinones Generates New Cell‐Penetrating Probes as Drug Carriers ()
ChemMedChem, EarlyView.
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Sulfated and Oxygenated Imidazoline Derivatives: Synthesis, Antioxidant Activity and Light‐Mediated Antibacterial Activity ()
ChemMedChem, EarlyView.
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Reduction‐Triggered Doxorubicin Delivery by Self‐Assembled Nanospheres of Lipoylated Caffeine ()
ChemMedChem, EarlyView.
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Preclinical Anticancer Activity of an Electron‐Deficient Organoruthenium(II) Complex ()
ChemMedChem, Accepted Article.
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Enhanced Efficacy of Gefitinib in Drug‐Sensitive and Drug‐Resistant Cancer Cell Lines after Arming with a Singlet Oxygen Releasing Moiety ()
ChemMedChem, EarlyView.
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Yicathins B and C and Analogues: Total Synthesis, Lipophilicity and Biological Activities ()
ChemMedChem, EarlyView.
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A Comparative Study of in vitro Assays for Predicting the Nonspecific Binding of PET Imaging Agents in vivo ()
ChemMedChem, Volume 15, Issue 7, Page 585-592, April 3, 2020.
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Synthesis, Molecular Docking, and Preliminary Evaluation of 2‐(1,2,3‐Triazoyl)benzaldehydes As Multifunctional Agents for the Treatment of Alzheimer's Disease ()
ChemMedChem, Volume 15, Issue 7, Page 610-622, April 3, 2020.
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Design, Synthesis, and Dual Evaluation of Quinoline and Quinolinium Iodide Salt Derivatives as Potential Anticancer and Antibacterial Agents ()
ChemMedChem, Volume 15, Issue 7, Page 600-609, April 3, 2020.
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Biodegradable Periodic Mesoporous Organosilica (BPMO) Loaded with Daunorubicin: A Promising Nanoparticle‐Based Anticancer Drug ()
ChemMedChem, Volume 15, Issue 7, Page 593-599, April 3, 2020.
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Tranylcypromine‐Based LSD1 Inhibitors: Structure‐Activity Relationships, Antiproliferative Effects in Leukemia, and Gene Target Modulation ()
ChemMedChem, Volume 15, Issue 7, Page 643-658, April 3, 2020.
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Comparative in vitro Studies of the Topoisomerase I Inhibition and Anticancer Activities of Metallated N‐Confused Porphyrins and Metallated Porphyrins ()
ChemMedChem, Volume 15, Issue 7, Page 632-642, April 3, 2020.
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Structure‐Based Design, Synthesis, and Biological Evaluation of Triazole‐Based smHDAC8 Inhibitors ()
ChemMedChem, Volume 15, Issue 7, Page 571-584, April 3, 2020.
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Covalent Complex of DNA and Bacterial Topoisomerase: Implications in Antibacterial Drug Development ()
ChemMedChem, Volume 15, Issue 7, Page 623-631, April 3, 2020.
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Cover Feature: A Comparative Study of in vitro Assays for Predicting the Nonspecific Binding of PET Imaging Agents in vivo (ChemMedChem 7/2020) ()
ChemMedChem, Volume 15, Issue 7, Page 560-560, April 3, 2020.
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Front Cover: Structure‐Based Design, Synthesis, and Biological Evaluation of Triazole‐Based smHDAC8 Inhibitors (ChemMedChem 7/2020) ()
ChemMedChem, Volume 15, Issue 7, Page 559-559, April 3, 2020.
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Elucidation of an Allosteric Mode of Action for a Thienopyrazole RORγt Inverse Agonist ()
ChemMedChem, Volume 15, Issue 7, Page 561-565, April 3, 2020.
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Shape Similarity by Fractal Dimensionality: An Application in the de novo Design of (−)‐Englerin A Mimetics ()
ChemMedChem, Volume 15, Issue 7, Page 566-570, April 3, 2020.
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Computationally Empowered Workflow Identifies Novel Covalent Allosteric Binders for KRASG12C ()
ChemMedChem, EarlyView.
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DISCOVERY OF NEW ANTIPROLIFERATIVE IMIDAZOPYRAZOLE ACYLHYDRAZONES ABLE TO INTERACT WITH MICROTUBULE SYSTEM ()
ChemMedChem, Accepted Article.
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Development of Therapeutic Gramicidin S Analogues Bearing Plastic β,γ‐Diamino Acids ()
ChemMedChem, Accepted Article.
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Total synthesis intermediates as a molecule treasure chest:  hit to leads with cytotoxic effect in leukemic cells ()
ChemMedChem, Accepted Article.
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Peptidomimetic Polo‐Box targeted inhibitors that engage PLK1 in tumor cells and are selective against the PLK3 tumor suppressor. ()
ChemMedChem, Accepted Article.
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Development and Structural Evaluation of N‐Alkylated trans‐2‐Phenylcyclopropylamine‐Based LSD1 Inhibitors ()
ChemMedChem, EarlyView.
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Aryloxy Triester Phosphoramidates as Phosphoserine Prodrugs: A Proof of Concept Study ()
ChemMedChem, EarlyView.
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Switchable fluorescence of doxorubicin for label‐free imaging of bioorthogonal drug release ()
ChemMedChem, Accepted Article.
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Asymmetric Disulfanylbenzamides as Irreversible and Selective Inhibitors of Staphylococcus aureus Sortase A ()
ChemMedChem, EarlyView.
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Discovery of Novel Autophagy Inhibitors and Their Sensitization Abilities for Vincristine‐Resistant Esophageal Cancer Cell Line Eca109/VCR ()
ChemMedChem, Accepted Article.
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Allosteric p97 Inhibitors Can Overcome Resistance to ATP‐Competitive p97 Inhibitors for Potential Anticancer Therapy ()
ChemMedChem, EarlyView.
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Small‐Molecule Inhibitors of METTL3, the Major Human Epitranscriptomic Writer ()
ChemMedChem, EarlyView.
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Synthesis, Labeling and Preclinical Evaluation of a Squaric Acid Containing PSMA Inhibitor Labeled with 68Ga: A Comparison with PSMA‐11 and PSMA‐617 ()
ChemMedChem, EarlyView.
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New Insights from Crystallographic Data: Diversity of Structural Motifs and Molecular Recognition Properties between Groups of IDO1 Structures. ()
ChemMedChem, Accepted Article.
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Resolving Binding Events on the Multifunctional Human Serum Albumin ()
ChemMedChem, EarlyView.
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5‐[2‐(N‐(Substituted phenyl)acetamide)]amino‐1,3,4‐thiadiazole‐2‐sulfonamides as Selective Carbonic Anhydrase II Inhibitors with Neuroprotective Effects ()
ChemMedChem, EarlyView.
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Rapid Discovery of Aspartyl Protease Inhibitors Using an Anchoring Approach ()
ChemMedChem, EarlyView.
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Discovery of a Class of Potent and Selective Non‐competitive Sentrin‐Specific Protease 1 Inhibitors ()
ChemMedChem, EarlyView.
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Synthesis and Evaluation of 2‐Aminothiophene Derivatives as Staphylococcus aureus Efflux Pump Inhibitors ()
ChemMedChem, EarlyView.
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Axially Chiral Cannabinols: A New Platform for Cannabinoid‐Inspired Drug Discovery ()
ChemMedChem, EarlyView.
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Binding and release of Fe(III) complexes from glucan particles for delivery of T1 MRI contrast agents ()
ChemMedChem, Accepted Article.
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Synthesis and SAR of tetracyclic inhibitors of protein kinase CK2 derived from furocarbazole W16 ()
ChemMedChem, Accepted Article.
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Synthesis and Biological Screening of new Lawson Derivatives as selective substrate‐based Inhibitors of Cytochrome bo3 Ubiquinol Oxidase from Escherichia coli ()
ChemMedChem, Accepted Article.
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Synthetic peroxides promote apoptosis of cancer cells inhibiting of P‐glycoprotein ABCB5 ()
ChemMedChem, Accepted Article.
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Recent Highlights in Anti‐Infective Medicinal Chemistry from South Africa ()
ChemMedChem, Accepted Article.
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Privileged Structures in Drug Discovery. Edited by Larry Yet ()
ChemMedChem, EarlyView.
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Further Investigations into Rigidity‐Activity Relationships in BisQAC Amphiphilic Antiseptics ()
ChemMedChem, EarlyView.
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Detection of HER2+ Breast Cancer Cells using Bioinspired DNA‐Based Signal Amplification ()
ChemMedChem, EarlyView.
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