Nature Reviews Drug Discovery

Genetic disorders: PI3K inhibitor reverses overgrowth syndrome ()

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Cancer: Releasing tumour suppressors ()

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Autoimmune disease: A human antibody selectively targets regulatory T cells ()

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Trends driving clinical trials into large clinical care settings ()

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Targeting the NLRP3 inflammasome in inflammatory diseases ()

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Cardiovascular disease: Improving cardiomyocyte contractility ()

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Infectious disease: Curbing cholera ()

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Anticancer therapy: Metabolic synthetic lethality ()

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