Organic letters

Synthesis of Ring-Fused Pyridinium Salts by Intramolecular Nucleophilic Aromatic Substitution Reaction and Their Optoelectronic Properties (Wed, 29 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00590
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Csp–Csp3 Bond Formation via Iron(III)-Promoted Hydroalkynylation of Unactivated Alkenes (Wed, 29 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00499
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General and Stereoselective Method for the Synthesis of Sterically Congested and Structurally Diverse P-Stereogenic Secondary Phosphine Oxides (Wed, 29 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00568
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Visible-Light-Induced Synthesis of Carbazoles by in Situ Formation of Photosensitizing Intermediate (Tue, 28 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00681
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Asymmetric Cascade Assembly of 1,2-Diaza-1,3-dienes and α,β-Unsaturated Aldehydes via Dienamine Activation (Tue, 28 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00636
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Synthesis of Sugar–Boronic Acid Derivatives: A Class of Potential Agents for Boron Neutron Capture Therapy (Tue, 28 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00382
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STAT3 Inhibitory Activity of Structurally Simplified Withaferin A Analogues (Tue, 28 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00332
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Aluminum-Catalyzed Cross-Coupling of Silylalkynes with Aliphatic C–F Bonds (Tue, 28 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00712
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Diazaphenoxazines and Diazaphenothiazines: Synthesis of the “Correct” Isomers Reveals They Are Highly Reactive Radical-Trapping Antioxidants (Tue, 28 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00615
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(+)-Thalianatriene and (−)-Retigeranin B Catalyzed by Sesterterpene Synthases from Arabidopsis thaliana (Tue, 28 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00586
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Enantioselective Synthesis of (−)-Acetylapoaranotin (Tue, 28 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00418
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Asymmetric [3 + 2] Cycloaddition of 3-Amino Oxindole-Based Azomethine Ylides and α,β-Enones with Divergent Diastereocontrol on the Spiro[pyrrolidine-oxindoles] (Tue, 28 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00625
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Three-Step Catalytic Asymmetric Total Syntheses of 13-Methyltetrahydroprotoberberine Alkaloids (Mon, 27 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00414
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Synthesis of Chiral γ-Lactams via in Situ Elimination/Iridium-Catalyzed Asymmetric Hydrogenation of Racemic γ-Hydroxy γ-Lactams (Mon, 27 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00651
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Hydroxy-Directed Enantioselective Hydroxyalkylation in the Carbocyclic Ring of Indoles (Mon, 27 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00354
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Asymmetric Synthesis of (−)-Pterocarine and (−)-Galeon via Chiral Phase Transfer-Catalyzed Atropselective Formation of Diarylether Cyclophane Skeleton (Mon, 27 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00570
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A Ligand-Directed Catalytic Regioselective Hydrocarboxylation of Aryl Olefins with Pd and Formic Acid (Mon, 27 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00507
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Palladium-Catalyzed Formal (5 + 2) Annulation between ortho-Alkenylanilides and Allenes (Mon, 27 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00467
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Macrophilone A: Structure Elucidation, Total Synthesis, and Functional Evaluation of a Biologically Active Iminoquinone from the Marine Hydroid Macrorhynchia philippina (Mon, 27 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00496
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Enantioselective Synthesis of 4H-Pyran via Amine-Catalyzed Formal (3 + 3) Annulation of δ-Acetoxy Allenoate (Mon, 27 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00658
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Tandem Spirocyclopropanation/Rearrangement Reaction of Vinyl p-Quinone Methides with Sulfonium Salts: Synthesis of Spirocyclopentenyl p-Dienones (Fri, 24 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00516
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Quaternary Carbon Center Forming Formal [3 + 3] Cycloaddition Reaction via Bifunctional Catalysis: Asymmetric Synthesis of Spirocyclohexene Pyrazolones (Fri, 24 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00610
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Transition Metal, Azide, and Oxidant-Free Homo- and Heterocoupling of Ambiphilic Tosylhydrazones to the Regioselective Triazoles and Pyrazoles (Fri, 24 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00313
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Nickel-Catalyzed Reduction of Secondary and Tertiary Amides (Fri, 24 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00683
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Platinum-Catalyzed Double Acylation of 2-(Aryloxy)pyridines via Direct C–H Activation (Fri, 24 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00423
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1,2-Benzothiazines from Sulfoximines and Allyl Methyl Carbonate by Rhodium-Catalyzed Cross-Coupling and Oxidative Cyclization (Fri, 24 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00488
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Pd-Catalyzed Direct ortho-C–H Arylation of Aromatic Ketones Enabled by a Transient Directing Group (Fri, 24 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00363
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Nickel-Catalyzed Aminoxylation of Inert Aliphatic C(sp3)–H Bonds with Stable Nitroxyl Radicals under Air: One-Pot Route to α-Formyl Acid Derivatives (Thu, 23 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00479
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Copper-Catalyzed, Stereoselective Cross-Coupling of Cyclic Allyl Boronic Acids with α-Diazoketones (Thu, 23 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00433
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Synthesis of 2-Acylbenzo[b]thiophenes via Cu-Catalyzed α-C–H Functionalization of 2-Halochalcones Using Xanthate (Thu, 23 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00462
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Intramolecular Aminoalkoxylation of Unfunctionalized Olefins via Intramolecular Iodoamination and Aziridinium Ion Ring-Opening Sequence (Thu, 23 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00284
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Stereospecific Nucleophilic Substitution of Enantioenriched Tertiary Benzylic Amines via in Situ Activation with Benzyne (Thu, 23 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00365
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Direct Approach to N-Substituted-2-Fluoroindoles by Sequential Construction of C–N Bonds from gem-Difluorostyrenes (Thu, 23 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00549
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Visible-Light-Mediated Catalytic Hydroacylation of Dialkyl Azodicarboxylates by Graphite Flakes (Thu, 23 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00519
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Stereoselective Palladium-Catalyzed Decarboxylative γ-Arylation of Acyclic β,γ-Unsaturated Carboxylic Acids (Thu, 23 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00512
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CuI Mediated One-Pot Cycloacetalization/Ketalization of o-Carbonyl Allylbenzenes: Synthesis of Benzobicyclo[3.2.1]octane Core (Thu, 23 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00630
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Aryl Fluorosulfate Trapped Staudinger Reduction (Thu, 23 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00406
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Asymmetric Total Synthesis of (−)-Aspidophylline A (Thu, 23 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00448
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Me3SiCF2Br-Self-Assisted Domino Reaction: Catalytic Synthesis of α,α-Difluorocyclopentanones from Methylvinylketones (Thu, 23 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00611
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Terrazoanthines, 2-Aminoimidazole Alkaloids from the Tropical Eastern Pacific Zoantharian Terrazoanthus onoi (Thu, 23 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00369
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Base Catalysis Enables Access to α,α-Difluoroalkylthioethers (Thu, 23 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00386
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Functionalized Tetrahydropyridines by Enantioselective Phosphine-Catalyzed Aza-[4 + 2] Cycloaddition of N-Sulfonyl-1-aza-1,3-dienes with Vinyl Ketones (Wed, 22 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00489
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Palladium-Catalyzed β-Mesylation of Simple Amide via Primary sp3 C–H Activation (Wed, 22 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00536
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Chemical Synthesis of Biosurfactant Succinoyl Trehalose Lipids (Wed, 22 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00550
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Linear Peptides Are the Major Products of a Biosynthetic Pathway That Encodes for Cyclic Depsipeptides (Wed, 22 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00545
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Enantioselective Synthesis of Dilignol Model Compounds and Their Stereodiscrimination Study with a Dye-Decolorizing Peroxidase (Wed, 22 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00587
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Transition-Metal-Free, Atom- and Step-Economic Synthesis of Aminoketopyrrolizines from Benzylamine, Acylethynylpyrroles, and Acylacetylenes (Tue, 21 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00408
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Rhodium(III)-Catalyzed Ortho-Alkenylation of Anilines Directed by a Removable Boc-Protecting Group (Tue, 21 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00569
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Access to Enantiopure 5-, 7-, and 5,7-Substituted cis-Decahydroquinolines: Enantioselective Synthesis of (−)-Cermizine B (Tue, 21 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00492
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Photo-oxidative Cross-Dehydrogenative Coupling-Type Reaction of Thiophenes with α-Position of Carbonyls Using a Catalytic Amount of Molecular Iodine (Tue, 21 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00428
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O6-Corona[6]arenes with Expanded Cavities for Specific Complexation with C70 (Tue, 21 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00409
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Base-Controlled Diastereoselective Synthesis of Either anti- or syn-β-Aminonitriles (Tue, 21 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00679
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High-Yielding and Divergent Paradigm for the Synthesis of D2h-Symmetric Octakis-Substituted Pentiptycenequinones (Tue, 21 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00606
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One-Pot Synthesis of a Mono-O,B,N-strapped BODIPY Derivative Displaying Bright Fluorescence in the Solid State (Mon, 20 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00435
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General Methodology for the Preparation of Unsymmetrical α-Linked Bisenones via Ligandless Cross-Coupling Reactions (Mon, 20 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00497
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(−)-Pseudodistomin E: First Asymmetric Synthesis and Absolute Configuration Assignment (Fri, 17 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00434
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Triggering a [2]Rotaxane Molecular Shuttle by a Photochemical Bond-Cleavage Strategy (Fri, 17 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00393
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Synthesis of Enantioenriched γ-Amino-α,β-unsaturated Esters Utilizing Palladium-Catalyzed Rearrangement of Allylic Carbamates for Direct Application to Formal [3 + 2] Cycloaddition (Fri, 17 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00471
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N-Doped Cationic PAHs by Rh(III)-Catalyzed Double C–H Activation and Annulation of 2-Arylbenzimidazoles with Alkynes (Thu, 16 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00478
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Deletion of a Histone Acetyltransferase Leads to the Pleiotropic Activation of Natural Products in Metarhizium robertsii (Thu, 16 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00476
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I2-Promoted Povarov-Type Reaction Using 1,4-Dithane-2,5-diol as an Ethylene Surrogate: Formal [4 + 2] Synthesis of Quinolines (Thu, 16 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00361
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Olefination with Sulfonyl Halides and Esters: Scope, Limitations, and Mechanistic Studies of the Hawkins Reaction (Thu, 16 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00517
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Transition-Metal-Free Direct C–H Arylation of Quinoxalin-2(1H)-ones with Diaryliodonium Salts at Room Temperature (Thu, 16 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00310
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Pinacol Coupling Strategy for the Construction of the Bicyclo[6.4.1]tridecane Framework of Schiglautone A (Thu, 16 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00288
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Synthesis of Substituted Benzo[b]thiophenes via Sequential One-Pot, Copper-Catalyzed Intermolecular C–S Bond Formation and Palladium-Catalyzed Intramolecular Arene–Alkene Coupling of Bis(het)aryl/alkyl-1,3-monothiodiketones and o-Bromoiodoarenes (Thu, 16 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00273
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Selective Lithiation, Magnesiation, and Zincation of Unsymmetrical Azobenzenes Using Continuous Flow (Wed, 15 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00460
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Synthesis of the ABC Tricyclic System of Daphnicyclidin A (Wed, 15 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00230
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Palladium-Catalyzed Cross-Coupling of N-Sulfonylaziridines and Alkenylboronic Acids: Stereospecific Synthesis of Homoallylic Amines with Di- and Trisubstituted Alkenes (Wed, 15 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00504
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Silver-Catalyzed Regioselective Fluorination of Carbonyl Directed Alkynes: Synthesis of α-Fluoroketones (Wed, 15 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00453
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Diastereoselective Synthesis of Dibenzo[b,d]azepines by Pd(II)-Catalyzed [5 + 2] Annulation of o-Arylanilines with Dienes (Wed, 15 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00503
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Total Synthesis of (±)-Grandilodine B (Wed, 15 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00591
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Synthesis and Properties of a Twisted and Stable Tetracyano-Substituted Tetrabenzoheptacene (Tue, 14 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00493
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Enantioselective Iridium-Catalyzed Allylic Alkylation Reactions of Masked Acyl Cyanide Equivalents (Tue, 14 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00449
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Dimethylzinc-Mediated Addition of Phenylacetylene to α-Diketones Catalyzed by Chiral Perhydro-1,3-benzoxazines (Tue, 14 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00252
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Copper-Catalyzed Selective ortho-C–H/N–H Annulation of Benzamides with Arynes: Synthesis of Phenanthridinone Alkaloids (Tue, 14 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00442
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Solvent-Dependent Self-Assembly and Crystal Structures of a Salen-Based Macrocycle (Tue, 14 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00264
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K2CO3-Mediated Cyclization and Rearrangement of γ,δ-Alkynyl Oximes To Form Pyridols (Tue, 14 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00389
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Palladium-Catalyzed Double Allylation of Sugar-Imines by Employing Tamaru–Kimura’s Protocol: Access to Unnatural Iminosugars (Tue, 14 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00441
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Direct Intermolecular C–H Functionalization Triggered by 1,5-Hydride Shift: Access to N-Arylprolinamides via Ugi-Type Reaction (Tue, 14 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00378
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Enantioselective Direct α-Arylation of Pyrazol-5-ones with 2-Indolylmethanols via Organo-Metal Cooperative Catalysis (Tue, 14 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00351
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Metal-Free Transamidation of Secondary Amides via Selective N–C Cleavage under Mild Conditions (Tue, 14 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00429
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Regio- and Stereoselective Synthesis of Functionalized Cyclopentene Derivatives via Mizoroki–Heck Reactions (Tue, 14 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00325
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Nickel-Catalyzed Synthesis of Primary Aryl and Heteroaryl Amines via C–O Bond Cleavage (Mon, 13 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00556
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Absolute Stereochemical Determination of Asymmetric Sulfoxides via Central to Axial Induction of Chirality (Mon, 13 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00495
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Nitrosocarbonyl–Henry and Denitration Cascade: Synthesis of α-Ketoamides and α-Keto Oximes (Mon, 13 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00482
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Construction of Fused Polyheterocycles through Sequential [4 + 2] and [3 + 2] Cycloadditions (Mon, 13 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00452
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Silver-Catalyzed Decarboxylative Bromination of Aliphatic Carboxylic Acids (Mon, 13 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00439
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Reversible Macrocyclization of Peptides with a Conjugate Acceptor (Fri, 10 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00451
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Correction to “Facile Synthesis of Halogenated Spiroketals via a Tandem Iodocyclization” (Fri, 10 Mar 2017)
Organic Letters DOI: 10.1021/acs.orglett.7b00643
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Bimane: A Visible Light Induced Fluorescent Photoremovable Protecting Group for the Single and Dual Release of Carboxylic and Amino Acids (Fri, 10 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00416
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Pd-Catalyzed Selective Synthesis of Cyclic Sulfonamides and Sulfinamides Using K2S2O5 as a Sulfur Dioxide Surrogate (Thu, 09 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00402
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Palladium-Catalyzed Formylation of Arylzinc Reagents with S-Phenyl Thioformate (Thu, 09 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00447
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Intramolecular Didehydro-Diels–Alder Reaction for the Synthesis of Benzo- and Dihydrobenzo-Fused Heterocycles (Tue, 07 Mar 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b00155
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