Organic letters

A Total Synthesis of the Antifungal Deoxyaminocyclitol Nabscessin B from l-(+)-Tartaric Acid (Fri, 08 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03495
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Lewis Base–Boryl Radicals Enabled the Desulfurizative Reduction and Annulation of Thioamides (Fri, 08 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03201
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Di-2-(2-oxindolin-3-ylidene)malononitrile Derivatives for N-Type Air-Stable Organic Field-Effect Transistors (Fri, 08 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03284
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Copper-Mediated Cascade C–H/N–H Annulation of Indolocarboxamides with Arynes: Construction of Tetracyclic Indoloquinoline Alkaloids (Fri, 08 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03580
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Total Synthesis of Huperzine R (Fri, 08 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03555
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Iridium-Catalyzed Hydrosilylation of Sulfur-Containing Olefins (Fri, 08 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b02940
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Cooperative Activating Effect of Tertiary Amine/DMSO on Elemental Sulfur: Direct Access to Thioaurones from 2′-Nitrochalcones under Mild Conditions (Fri, 08 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03547
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Rh-Catalyzed Asymmetric Hydrogenation of β-Branched Enol Esters for the Synthesis of β-Chiral Primary Alcohols (Fri, 08 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03469
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Enantioselective Synthesis of Spliceostatin G and Evaluation of Bioactivity of Spliceostatin G and Its Methyl Ester (Fri, 08 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03456
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Combining Visible-Light-Photoredox and Lewis Acid Catalysis for the Synthesis of Indolizino[1,2-b]quinolin-9(11H)-ones and Irinotecan Precursor (Thu, 07 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03395
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One-Pot Synthesis of Difluoromethyl Thioethers from Thiourea and Diethyl Bromodifluoromethylphosphonate (Thu, 07 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03538
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Rh(III)-Catalyzed Cascade Annulations To Access Isoindolo[2,1-b]isoquinolin-5(7H)-ones via C–H Activation: Synthesis of Rosettacin (Thu, 07 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03509
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Photocatalytic Synthesis of γ-Lactones from Alkenes: High-Resolution Mass Spectrometry as a Tool To Study Photoredox Reactions (Thu, 07 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03256
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Silver(I)- and Base-Mediated [3 + 3]-Cycloaddition of C,N-Cyclic Azomethine Imines with Aza-oxyallyl Cations (Thu, 07 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03344
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Approach to Introducing Substituent on the Dipole Conjugate Chain: The D−π–A Methine Chain Electrophilic Substitution (Thu, 07 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03345
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Scalable Electrochemical Dehydrogenative Lactonization of C(sp2/sp3)–H Bonds (Thu, 07 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03617
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Palladium- and Nickel-Catalyzed Decarbonylative C–S Coupling to Convert Thioesters to Thioethers (Thu, 07 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03305
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Asymmetric Synthesis of Rupestonic Acid and Pechueloic Acid (Wed, 06 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03459
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Exploring Tandem Ruthenium-Catalyzed Hydrogen Transfer and SNAr Chemistry (Wed, 06 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03441
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Copper-Mediated Annulation of Phosphorus-Containing Arenes with Alkynes: An Approach to Phosphindolium Salts (Wed, 06 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03394
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Organocatalytic Asymmetric Synthesis of Spiro-oxindole Piperidine Derivatives That Reduce Cancer Cell Proliferation by Inhibiting MDM2–p53 Interaction (Wed, 06 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03516
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Catalytic Enantioselective Synthesis of (−)-Podophyllotoxin (Wed, 06 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03236
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Direct Carboxylation of the Diazo Group ipso-C(sp2)–H bond with Carbon Dioxide: Access to Unsymmetrical Diazomalonates and Derivatives (Wed, 06 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03573
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Single or Synergistic Kinetic Resolutions of Chiral Allylalanes: Two Complementary Routes for the Asymmetric Synthesis of Syn Homoallylamines (Wed, 06 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03455
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Synthesis of N,S-Heterocycles and Dithiocarbamates by the Reaction of Dithiocarbamic Acids and S-Alkyl Dithiocarbamates with Nitroepoxides (Wed, 06 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03501
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Carbonyl Iron Powder: A Reagent for Nitro Group Reductions under Aqueous Micellar Catalysis Conditions (Tue, 05 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03216
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Csp2–Csp2 and Csp2–N Bond Formation in a One-Pot Reaction between N-Tosylhydrazones and Bromonitrobenzenes: An Unexpected Cyclization to Substituted Indole Derivatives (Tue, 05 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03422
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Ring-Opening Diarylation of Siloxydifluorocyclopropanes by Ag(I) Catalysis: Stereoselective Construction of 2-Fluoroallylic Scaffold (Tue, 05 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03254
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Bicyclization of Azomethine Ylide: Access to Highly Functionalized 3H-Pyrrolo[2,3-c]quinolines (Tue, 05 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03434
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Metal-Free Diaryl Etherification of Tertiary Amines by Ortho-C(sp2)–H Functionalization for Synthesis of Dibenzoxazepines and -ones (Tue, 05 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03328
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Total Synthesis of (+)-Gliocladin C Based on One-Pot Construction of a 3a-(3-Indolyl)pyrroloindoline Skeleton by Sulfonium-Mediated Cross-Coupling of Tryptophan and Indole (Tue, 05 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03293
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Synthesis of Oligo-(alkyne-triplet)peptide Constructs (Tue, 05 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03231
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Dramatic Acceleration of an Acyl Transfer-Initiated Cascade by Using Electron-Rich Amidine-Based Catalysts (Mon, 04 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03044
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Total Synthesis of Propolisbenzofuran B (Mon, 04 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b02732
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Controlling the C(sp3)–C(sp2) Axial Conformation in the Enantioselective Friedel–Crafts-Type Alkylation of β-Naphthols with Inden-1-ones (Mon, 04 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03415
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Directed Aromatic C–H Activation/Acetoxylation Catalyzed by Pd Nanoparticles Supported on Graphene Oxide (Mon, 04 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b02967
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A Multicomponent Route to Functionalized Amides and Oxazolidinones (Fri, 01 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03470
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Ni-Catalyzed Dimerization and Arylation of Diarylacetylenes with Arylboronic Acids (Fri, 01 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03398
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Synthesis of 2-Pyridinemethyl Ester Derivatives from Aldehydes and 2-Alkylheterocycle N-Oxides via Copper-Catalyzed Tandem Oxidative Coupling–Rearrangement (Fri, 01 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03446
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Asymmetric Total Synthesis of (+)-Intricenyne via an Endocyclization Route to Oxocane Skeleton (Fri, 01 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03370
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3,4,5-Trimethylphenol and Lewis Acid Dual-Catalyzed Cascade Ring-Opening/Cyclization: Direct Synthesis of Naphthalenes (Fri, 01 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03392
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Esters as Alkynyl Acyl Ammonium and Azolium Precursors: A Formal [2 + 3] Annulation with Amidomalonates via Lewis Base/Lewis Acid Cooperative Catalysis (Fri, 01 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03453
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Copper-Catalyzed Substitution of α-Triflyloxy Nitriles and Esters with Silicon Nucleophiles under Inversion of the Configuration (Fri, 01 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03279
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Organo-Catalyzed Asymmetric Michael–Hemiketalization–Oxa-Pictet–Spengler Cyclization for Bridged and Spiro Heterocyclic Skeletons: Oxocarbenium Ion as a Key Intermediate (Fri, 01 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03341
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Highly Diastereoselective Cationic Cyclization Reactions Convert a Common Monocyclic Enone to Bicyclic Precursors for the Synthesis of Retigeranic Acids A and B (Fri, 01 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03412
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Iodobenzene-Catalyzed Ortho-Dearomatization and Aromatization-Triggered Rearrangement of 2-Allylanilines: Construction of Indolin-3-ylmethanols with High Diastereoselectivities (Fri, 01 Dec 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b02986
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Ruthenium(II)-Catalyzed Redox-Neutral Oxidative Cyclization of Benzimidates with Alkenes with Hydrogen Evolution (Thu, 30 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03405
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Iron(III)-Catalyzed Ortho-Preferred Radical Nucleophilic Alkylation of Electron-Deficient Arenes (Thu, 30 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03244
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Palladium-Catalyzed Oxidative Borylation of Allylic C–H Bonds in Alkenes (Thu, 30 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03296
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Total Synthesis of Four Isomers of the Proposed Structures of Cryptorigidifoliol K (Thu, 30 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03174
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Antiprotozoal Spirombandakamines A1 and A2, Fused Naphthylisoquinoline Dimers from a Congolese Ancistrocladus Plant (Thu, 30 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03473
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Synthesis of Functionalized Benzo[g]indoles and 1-Naphthols via Carbon–Carbon Triple Bond Breaking/Rearranging (Thu, 30 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03410
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Reversibly Tunable White-Light Emissions of Styrylpyridiniums with Cucurbiturils in Aqueous Solution (Thu, 30 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03377
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Molecular Oxygen-Mediated Minisci-Type Radical Alkylation of Heteroarenes with Boronic Acids (Wed, 29 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03297
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Ruthenium-Catalyzed C–H Activation of Salicylaldehyde and Decarboxylative Coupling of Alkynoic Acids for the Selective Synthesis of Homoisoflavonoids and Flavones (Wed, 29 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03325
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Silver-Catalyzed Cyclopropanation of Alkenes Using N-Nosylhydrazones as Diazo Surrogates (Wed, 29 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03374
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Synthesis of the Cancer-Associated KH-1 Antigen by Block Assembly of Its Backbone Structure Followed by One-Step Grafting of Three Fucose Residues (Wed, 29 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03275
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Molecular-Iodine-Catalyzed Cyclization of 2-Alkynylanilines via Iodocyclization–Protodeiodination Sequence (Wed, 29 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03497
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Focused Genome Mining of Structurally Related Sesterterpenes: Enzymatic Formation of Enantiomeric and Diastereomeric Products (Wed, 29 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03418
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Electrocatalytic Dehydrogenative Esterification of Aliphatic Carboxylic Acids: Access to Bioactive Lactones (Wed, 29 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03333
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Phosphine-Catalyzed Asymmetric Synthesis of α-Quaternary Amine via Umpolung γ-Addition of Ketimines to Allenoates (Tue, 28 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03262
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Ruthenium-Catalyzed meta-Carboxylation (Tue, 28 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03387
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Convergent Synthesis of Digalactosyl Diacylglycerols (Tue, 28 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03043
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A Fe(III)/NaBH4-Promoted Free-Radical Hydroheteroarylation of Alkenes (Tue, 28 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03313
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Oxidative Dehomologation of Aldehydes with Oxygen as a Terminal Oxidant (Tue, 28 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03512
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Palladium-Catalyzed Direct C–H Functionalization of Indoles with the Insertion of Sulfur Dioxide: Synthesis of 2-Sulfonated Indoles (Tue, 28 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03365
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Enantioselective Total Synthesis of (+)-Gephyrotoxin 287C (Tue, 28 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03381
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Bismuth Triflate-Catalyzed Vinylogous Nucleophilic 1,6-Conjugate Addition of para-Quinone Methides with 3-Propenyl-2-silyloxyindoles (Tue, 28 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03433
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Lewis Base-Catalyzed One-Pot Cascade Sequences of O-Alkenyl-Substituted Cyanohydrins: Diastereoselective Synthesis of Multisubstituted Dihydrofurans (Tue, 28 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03301
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Oxamidation of Unsaturated O-Alkyl Hydroxamates: Synthesis of the Madangamine Diazatricylic (ABC Rings) Skeleton (Tue, 28 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03283
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Ru/Ni Dual Catalytic Desulfinative Photoredox Csp2–Csp3 Cross-Coupling of Alkyl Sulfinate Salts and Aryl Halides (Tue, 28 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03280
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Catalytic Asymmetric Cascade Using Spiro-Pyrrolidine Organocatalyst: Efficient Construction of Hydrophenanthridine Derivatives (Tue, 28 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03330
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Palladium-Catalyzed Domino Alkenylation/Amination/Pyridination Reactions of 2-Vinylanilines with Alkynes: Access to Cyclopentaquinolines (Tue, 28 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03164
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Synthesis of 4-(Trifluoromethyl)cyclopentenones and 2-(Trifluoromethyl)furans by Reductive Trifluoroacetylation of Ynones (Tue, 28 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03302
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Synthesis of Vinyl-, Allyl-, and 2-Boryl Allylboronates via a Highly Selective Copper-Catalyzed Borylation of Propargylic Alcohols (Tue, 28 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03294
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General Method for the Suzuki–Miyaura Cross-Coupling of Primary Amide-Derived Electrophiles Enabled by [Pd(NHC)(cin)Cl] at Room Temperature (Mon, 27 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03191
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Cu-Catalyzed Enantioselective Boron Addition to N-Heteroaryl-Substituted Alkenes (Mon, 27 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03327
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Crossover-Annulation/Oxygenation Approach to Functionalized Phenanthridines by Palladium–Copper Relay Catalysis (Mon, 27 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03427
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TBAI/TBHP-Mediated Cascade Cyclization toward Sulfonylated Indeno[1,2-c]quinolines (Mon, 27 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03246
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Synthesis of Poly-Ubiquitin Chains Using a Bifunctional Ubiquitin Monomer (Mon, 27 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03085
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Synthesis of the C(1)–C(13) Fragment of Leiodermatolide via Hydrogen-Mediated C–C Bond Formation (Thu, 23 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03351
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Rh-Catalyzed Conversion of 3-Diazoindolin-2-imines to 5H-Pyrazino[2,3-b]indoles with Photoluminescent Properties (Wed, 22 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03211
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Lewis Acid Mediated “endo-dig” Hydroalkoxylation–Reduction on Internal Alkynols for the Stereoselective Synthesis of Cyclic Ethers and 1,4-Oxazepanes (Wed, 22 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03241
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Synthesis of N-Oxyureas by Substitution and Cope-Type Hydroamination Reactions Using O-Isocyanate Precursors (Wed, 22 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03288
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Copper(II)-Catalyzed Oxidative Coupling of Anilines, Methyl Arenes, and TMSN3 via C(sp3/sp2)–H Functionalization and C–N Bond Formation (Wed, 22 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03264
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Rhodium-Catalyzed Synthesis of Sulfur Ylides via in Situ Generated Iodonium Ylides (Wed, 22 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03413
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A Twist of the Twist Mechanism, 2-Iodoxybenzoic Acid (IBX)-Mediated Oxidation of Alcohol Revisited: Theory and Experiment (Wed, 22 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03167
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Correction to Methods for the Synthesis of Substituted Azetines (Wed, 22 Nov 2017)
Organic Letters DOI: 10.1021/acs.orglett.7b03520
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Highly Enantioselective Asymmetric Hydrogenation of Carboxy-Directed α,α-Disubstituted Terminal Olefins via the Ion Pair Noncovalent Interaction (Wed, 22 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b02972
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Phenanthrene Synthesis via Chromium-Catalyzed Annulation of 2-Biaryl Grignard Reagents and Alkynes (Wed, 22 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03342
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Divergent Access to Functionalized Pyrrolidines and Pyrrolines via Iridium-Catalyzed Domino-Ring-Opening Cyclization of Vinyl Aziridines with β-Ketocarbonyls (Wed, 22 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03232
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Highly Enantioselective Synthesis of Chiral Cyclopropyl Nucleosides via Catalytic Asymmetric Intermolecular Cyclopropanation (Wed, 22 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03110
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Highly Diastereo- and Enantioselective Palladium-Catalyzed [3 + 2] Cycloaddition of Vinyl Epoxides and α,β-Unsaturated Ketones (Wed, 22 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03386
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Scalable Synthesis of Trifluoromethylated Imidazo-Fused N-Heterocycles Using TFAA and Trifluoroacetamide as CF3-Reagents (Tue, 21 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b03291
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Organic CO Prodrugs Activated by Endogenous ROS (Tue, 07 Nov 2017)
TOC Graphic Organic Letters DOI: 10.1021/acs.orglett.7b02775
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Retraction of “Transition-Metal-Free C–CN/C–H Cross-Coupling: Effect of Cyano Group” (Mon, 11 Sep 2017)
Organic Letters DOI: 10.1021/acs.orglett.7b02473
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