Home
Organic reaction
■ Palladium-catalyzed coupling reactions
►Buchwald-hartwig amination
►Fukuyama reaction
►Heck reaction
►Hiyama coupling
►Kumada coupling
►Liebeskind-Srogl coupling
►Negishi coupling
►Sonogashira reaction
►Stille reaction
►Suzuki reaction
■ Names reactions
►A
►B
►C
►D
►E
►F
►G
►H
►I
►J
►K
►L
►M
►N
►O
►P
►R
►S
►T
►U
►V
►W
►Y
►Z
■ Multi-component reactions
►Biginelli reaction
►Bucherer-Bergs reaction
►Gewald reaction
►Hantzsch synthesis
►Mannich reaction
►Passerini reaction
►Strecker reaction
►Ugi reaction
■ Heterocycles
5-Membered rings
6-Membered rings
Fused rings
Organic synthesis
■ Protecting Groups
►Alcohol protecting groups
Ester
Ether
Ether silyl
►Amine protecting groups
Amine
Amide
Carbamate
Sulfonamide
►Carboxylic acid protecting groups
►Carbonyl protecting groups
■ Coupling Reagents in Peptide Synthesis
►Aminium
►Carbodiimides
►Phosphonium
►Uronium
►Other Couplig Reagents
■ Functional Group Synthesis
►Aldehydes
►Amides
►Amines
►Esters
►Halides derivatives
►Ketones
►Thioamides
■ Aminos acids
►Naturals aminos acids
►Homo aminos acids
►Beta-aminos acids
►Gamma-aminos acids
►Alkyls aminos acids
►Aryls aminos acids
Peptide synthesis
Patent Highlights
►Pfizer
WO2010035166
WO2010015972
WO2010016005
WO2010032200
WO2010007561
WO2010013161
WO2010038165
WO2010049841
WO2010052625
WO2010058314
WO2010058333
WO2010061329
WO2010038167
►Roche
WO2010020548
WO2010026110
WO2010043515
WO2010043513
WO2010018112
WO2010018113
WO2010026075
WO2010046273
WO2010028981
WO2010031708
WO2010031713
WO2010034649
WO2010034656
WO2010034657
WO2010034671
WO2010040661
WO2010040663
WO2010049303
WO2010049331
WO2010054961
WO2010054968
WO2010055004
WO2010055005
WO2010055006
WO2010030703
WO2010057795
WO2010063610
WO2010063634
WO2010031707
►Merck
WO2010022850
WO2010056717
WO2010056708
WO2010056496
WO2010056564
WO2010056567
WO2010056788
WO2010059773
WO2010062415
WO2010063352
WO2010065384
►Galapagos
WO2010010184
WO2010010186
WO2010010187
WO2010010189
WO2010029119
WO2010149769
►Astrazeneca
WO2010049731
WO2010033074
WO2010024769
WO2010019097
WO2010007427
WO2010005385
WO2010020810
WO2010001169
WO2010068172
WO2010068171
WO2010067125
WO2010067123
WO2010067102
WO2010062245
WO2010061208
WO2010056196
WO2010056195
WO2010056194
WO2010055348
WO2010053438
WO2010049073
WO2010043893
WO2010039079
WO2010038081
WO2010038060
WO2010015849
►GSK
WO2010036831
WO2010045309
WO2010011818
WO2010022307
WO2010022308
WO2010011912
WO2010025087
WO2010037760
WO2010043714
WO2010014593
WO2010010133
WO2010007074
WO2010007072
WO2010039911
WO2010039913
WO2010039922
WO2010007073
WO2010065383
WO2010037723
WO2010011917
WO2010015653
WO2010019637
WO2010007032
WO2010011914
WO2010045451
WO2010015652
WO2010049366
WO2010059774
WO2010059658
WO2010059555
WO2010059552
WO2010059549
WO2010062578
WO2010068262
WO2010135504
WO2010102958
►Novartis
WO2009158431
WO2010026122
WO2010026121
WO2010006191
WO2010007027
WO2010026124
WO2010015655
WO2010020675
WO2010007046
WO2010015628
WO2010029082
WO2010007120
WO2010003976
WO2010031750
WO2010043584
WO2010015613
WO2010002655
►Sanofi-aventis
WO2010000353
WO2010003624
WO2010004197
WO2010004198
WO2010004215
WO2010006704
WO2010007316
WO2010007317
WO2010007318
WO2010010288
WO2010012964
WO2010013078
WO2010018327
WO2010018328
WO2010018329
WO2010022196
WO2010025856
WO2010028761
WO2010049635
WO2010055267
WO2010063929
WO2010065571
WO2010065798
WO2010065803
WO2010070237
WO2010070238
►Janssen
WO2010000456
WO2010002774
WO2010008761
►Amgen
WO2010108074
WO2010126895
WO2010132589
Synthetic protocols
■ Functionals groups
Primary amine
Secondary amine
Aldehyde
Azido
Carboxylic acid
Cyanide
Epoxide
Ester
Ether
Hydroxyl
Ketone
Mesyl
Methoxy
Tosyl
Sulfonamide
■ Palladium-Catalyzed Coupling Reaction
Buchwald-Hartwig amination
Heck reaction
Negishi coupling
Sonogashira reaction
Stille reaction
Suzuki reaction
■ Protecting groups
N-Boc
N-Cbz
N-SEM
N-THP
N-TFA
N-DMPM
O-TBDMS
O-Bn
■ Coupling Reagents in Amide Synthesis
■ Multi-component reaction
Strecker reaction
Ugi reaction
■ Microwave synthesis
Alkyl amine synthesis
Buchwald-Hartwig amination
Cyanide synthesis
Ether synthesis
Stille reaction
Suzuki reaction
Thioether synthesis
Urea synthesis
■ Parallel synthesis
Reductive amination
Alkylation / deprotection / alkylation
Organic and Medicinal Chemistry News
Angewandte Chemie International Edition
Archiv der Pharmazie
Chem. Commun.
Chemical Reviews
Green Chem.
Journal of the American Society
Organic letters
Tetrahedron
Tetrahedron: Asymmetry
Tetrahedron Letters
The Journal of Organic Chemistry
ACS Chemical Biology
Bioorganic & Medicinal Chemistry
ACS Medicinal Chemistry Letters
Bioorganic & Medicinal Chemistry Letters
Chemistry & Biology
ChemMedChem
Drug Discovery Today
Nature Chemical Biology
Nature Reviews Drug Discovery
Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry
Organic & Biomolecular Chemistry
MedChemComm
Pharmaceuticals Patents News
Pfizer
Novartis
Hoffmann-La Roche
Merck
Sanofi
Johnson and Johnson
Gilead
GSK
Abbvie
AMGEN
Allergan
TEVA
BMS
Lilly
Bayer
Novo Nordisk
Boehringer Ingelheim
Takeda
Celgene
Astellas Pharma
Shire
Mylan
Biogen Idec
Daiichi Sankyo
Merck KGaA
Valeant Pharma
Otsuka
Sun pharma
Eisai
Servier
Endo Health Pharma
UCB
Abbott
Chugai Pharma
Actelion
Ferring Pharma
Universities and Institutes Patents News
Columbia university
Emory university
Havard university
Johns Hopkins university
Michigan university
Northwestern university
Princeton university
The university of California
The university of Texas
The university of UTAH
University of Pennsylvania
Yale University
Caltech
CNRS
CSIR
Dana-Farber
KRICT
MIT
Scripps
Sloan-Kettering
Contact
Home
Organic reaction
Organic synthesis
Peptide synthesis
Patent Highlights
►Pfizer
►Roche
WO2010020548
WO2010026110
WO2010043515
WO2010043513
WO2010018112
WO2010018113
WO2010026075
WO2010046273
WO2010028981
WO2010031708
WO2010031713
WO2010034649
WO2010034656
WO2010034657
WO2010034671
WO2010040661
WO2010040663
WO2010049303
WO2010049331
WO2010054961
WO2010054968
WO2010055004
WO2010055005
WO2010055006
WO2010030703
WO2010057795
WO2010063610
WO2010063634
WO2010031707
►Merck
►Galapagos
►Astrazeneca
►GSK
►Novartis
►Sanofi-aventis
►Janssen
►Amgen
Synthetic protocols
Organic and Medicinal Chemistry News
Pharmaceuticals Patents News
Universities and Institutes Patents News
Contact
WO2010054961 Spiro-5,6-dihydro-4H-2,3,5,10B-tetraaza-benzo[E]azulenes
WO2010054961.pdf
Adobe Acrobat Document
3.1 MB
Download
Biological target:
Vasopressin:
V1a
Activity:
antagonist
Site Search