Tuberculosis

(6,7-dihydro-2-nitro-5H-imidazol[2,1-b][1,3]oxazin-6-yl) amide compounds, preparation methods and uses thereof (Fri, 07 Jun 2013)
<p id="p-0001" num="0000">(6,7-Dihydro-2-nitro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)amide compounds of formula (I), and their pharmaceutically acceptable salts, preparation methods and pharmaceutical compositions thereof are disclosed, wherein m and R are defined as in the description. The uses of the compounds in preparing medicaments for treating infectious diseases caused by <i>Mycobacterium tuberculosis</i>, especially infectious diseases caused by multi-drug resistance <i>Mycobacterium tuberculosi </i>are also disclosed.</p>
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(6,7-DIHYDRO-2-NITRO-5H-IMIDAZOL[2,1-B][1,3]OXAZIN-6-YL) AMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF (Thu, 28 Mar 2013)
(6,7-Dihydro-2-nitro-5H-imidazo [2,1-b][1,3]oxazin-6-yl)amide compounds of formula (I), and their pharmaceutically acceptable salts, preparation methods and pharmaceutical compositions thereof are disclosed, wherein m and R are defined as in the description. The uses of said compounds in preparing medicaments for treating infectious diseases caused by Mycobacterium tuberculosis, especially infectious diseases caused by multi-drug resistance Mycobacterium tuberculosi are also disclosed.
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PEPTIDES ANTAGONISTS FOR INHIBITING HEAT SHOCK PROTEIN (HSP 16.3) OF MYCOBACTERIUM TUBERCULOSIS (Thu, 08 Mar 2007)
The present invention provides peptide antagonists of Hsp16.3, a chaperon protein 5 necessary for the survival of <i>Mycobacterium tuberculosis </i>in the dormant phase is described.
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Sulfoglycolipid antigens, their extraction from mycobacterieum tuberculosis, and their use against tuberculosis (Thu, 21 Oct 2004)
The present invention relates to compounds of the following general formula: <CHEM> wherein R1 and R2 are fatty acyl groups, a process to extract them from Mycobacterium tuberculosis, and their use in the treatment or the prophylaxis of tuberculosis.
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CARBOHYDRATE COMPLEX EXTRACTED FROM MYCOBACTERIUM TUBERCULOSIS AND PROCESS FOR THE PREPARATION THEREOF (Thu, 13 Apr 2000)
A carbohydrate complex, which is a mixture of low molecular-weight polysaccharides of an arabinomannan structure extracted from $i(Mycobacterium tuberculosis), is highly effective in treating various cancer patients without incurring any adverse side effects.
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